The Changes Of Cerebrovascular Hemodynamic Index In Patients With Acute Hemorrhagic Stroke

Objective: To study the changes of cerebrovascular hemodynamic index in patients with acute hemorrhagic stroke within 2 weeks of disease onset by consecutive detection.Methods: We selected 71 patients with acute hemorrhagic stroke as the study group who were hospitalized within 24 hours after onset in the 1st 3rd 5th 7th 9th 11th 13th 15th day of hospitalization and prior to the usage of dehydrant. We selected 30 normal people as the control group. We collected the data of cerebrovascular hemodynamic index(CVDI) including cerebral blood flow and velocity, cerebrovascular resistance(R), cerebrovascular elasticity ,dynamic resistance(DR) and critical pressure(CP) for each patient . We compared the data between the study group and control group ,also we compared the data in the different time after disease onset and the data of affected side and non-affected side by using SPSS software.Results: The total cerebral blood flow and velocity of the study group were significantly lower than the control group at the different time after disease onset. The cerebrovascular resistance, cerebrovascular elasticity, dynamic resistance and critical pressure were significantly higher than the control group at the different time, and there were significantly difference among the data of different time. The data of CVDI have no difference between the affected side and non-affected side.Conclusion :In the acute hemorrhagic stroke, ischemic change was occurred in the two sides of brain hemisphere within 2 weeks, the cerebrovascular elasticity was evidently decreased within the first week and partly restored after 2 weeks; the cerebrovascular resistance and critical pressure were evidently increased within 3 days and decreased gradually after 1 week, the function of cerebrovascular regulation was obviously deteriorated in the first week and partly recovered in the second week. It suggests that the consecutive detecting of CVDI is useful to find the regularity of cerebral circulation of the different time in acute hemorrhagic stroke and helpful for its clinical treatment.