| AIM: Viable but stunned myocardium which is reversible exists after coronary reperfusion in patients with acute myocardial infarction. The regional systolic function of ischemic myocardium may recover completely after reperfusion. So it is very important for therapy or prediction to evaluate the vital myocardium and the cardial funtion. Integrated Backscatter is a new technique which can diagnosis without trauma. It can show the changes in tissue via the video signal which scatters by the tissue. Previous studies demonstrated that integrated backscatter parameters can predict the myocardial viability as early as possible, when integrated backscatter is regarded as a new technique which can assess the pathological changes in myocardium. The purpose of present study is to quantitatively assess the outcomes of patients with acute myocaidial infarction by integrated backscatter (IBS) who received percuataneous transluminal coronary angioplasty and primary (PTCA) is of great value for the patients with AMI..Methods: 36 patients with the first AMI who underwent PTCA therapy were divided into two groups according to the interval between sympton onset and angioplasty: <4 hrs (group A), >4 hrs (group B). We use HP5500 ultrasonic diagnostic machine to investigated the changes of calibrated myocardial integrated backscatter (IBS%), magnitude of cyclic variation in integrated backscatter (CVIB), calibration of delayed time of CVIB (DTCV%), and the velocity of endocardial motion of the whole systolic period (VSEM) 30 days after the PTCA.Result: The thirty days after reperfusion, the infracted myocardium that was evaluated by integrated backscatter (IBS) in group A was no significant difference compared with the normalized myocardium (p>0.05). The infracted myocardium that was evaluated by IBS in group B was significant difference compared with the normal myocardium and group A(P<0.01 0.05). The infracted myocardium withcalibrated CVIB in group A was lower than that of normal myocardium(p<0.01), the infracted myocardium with calibrated CVIB in group B was lower than that of normal myocardium and A group (p<0.01, p<0.05).The infracted myocardium of DTCV% in group A and group B was no significant difference than those of normal myocardium (p>0.05). The infracted myocardium of VSEM in group A was lower than that of normal myocardium(p<0.01), the infracted myocardium of in group B waslower than that of normal myocardium and group A(p<0.01, p<0.05). Conclusions:1. Early reperfusion (less 4 hrs after myocardial infarction) has good theraputiceffection on patients with first AMI.2. Integrated backscatter can predict the vital myocardium early.3. Both integrated backscatter and color kinesis can evaluate the outcomes of reperfusion in acute myocardial infarction, so they are worth for clinical use.
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