The Change Of PaCO₂ During Anesthesia And Recovery Time Of Laparoscopic Cholecystectomy

Objective: To study the change of PaCO2 during anesthesia period and after the release from pneumoperitoneum.Methods: Twenty ASA I ~ II patients undergoing cholecystectomy were randomly divided into two groups of ten: group A received laparoscopic cholecystectomy and group B received abdominal cholecystectomy. All patients' arterial patial pressure of carbon dioxide (PaCO2) were examined respectively via radialis arteria 5 minutes before induction, 5 minutes before insufflation or abdominal incision, 10,15,20,25,30 minutes after insufflation or abdominal incision, and 10,15,20,25,30 minutes after the release from pneumoperitoneum or operation.Results: (1) In group A, in comparison with 5 minutes before induction, patients' PaCO2 were increased 10 minutes after insufflation (PO.05), but they were still in normal range (P>0.05). While 15 minutes later PaCO2 were significantly increased (PO.01) and reached the highest point at 20 minutes after insufflation (PO.01). (2) Patients' PaCO2 in group A were remarkably increased at 5,10,15,20 and 25 minutes after the release from insufflation compared to 5 minutes before induction (P<0.01), while they fell to normal range 30 minutes after insufflation (P>0.05), but it was still higher than the value before anesthesia (P<0.01). (3) PaCO2 in group A were markedlyincreased in comparison with group B during operating time (P<0.01) andafter release from insufflation or operation (P<0.01).Conclusion: (1) During the anesthesia time of laparoscopic cholecystect-omy, PaCO2 were obviously increased 15 minutes after intra-abdominal CO2insufflation and reached the peak at 20 minutes. (2) PaCO2 decreased tonormal range 30 minutes after release from insufflation.