Clinical Application Of Advanced Hydrophobic Acrylic Intraocular Lens Sensar AR40e And The Comparison Between Sensar AR40e And Silicone Intraocular Lens

Objective: To observe and evaluate the clinical effect of advanced hydrophobicacrylic intraocular lens (IOL) Sensar AR40e and the comparison between advancedacrylic IOL and silicone IOL.Methods: A total of 49 hospitalized cataract patients (98 eyes) from September 2002to September 2003 were selected to attend this study. All cases were undergonephacoemulsification and IOLs implantation under topical anesthesia. One eye ofeach case used Sensar AR40e IOL randomly and the other eye used silicone IOL(AQ-110NV or SI40NB). They were observed and compared with those of siliconeIOLs that the properties of implantation of Sensar AR40e IOLs,complications such asbreak of IOL loops or rupture of posterior capsule in operations, the changes ofvisual acuity, anterior chamber flare, location of IOLs and posterior capsularopacification after operations. All operations were performed by three surgeons andthe postoperative treatments were standardized. Follow-up was 6 months.Results: The properties of implantation of the Sensar AR40e IOL were very well forthat it could be implanted easily with IOL folder and it outspread in the capsule gently.Neither loops broke nor optic area damaged when Sensar AR40e IOLs wereimplanted while it happened in 3 cases and 1 case, respectively, in implantations ofsilicone IOLs. Posterior capsule rupture occurred in 2 eyes in each group (Sensar - 4 -第二军医大学 学位论文AR40e IOL group or silicone IOL group). Mean uncorrected distance vision 1 weekafter the operation was 0.58±0.18 in Sensar AR40e IOL group and was 0.52±0.18 insilicone IOL group. Mean best-corrected distance visual acuity 1 month, 3 months and6 months after operation were 0.77±0.19, 0.77±0.20 and 0.75±0.26 respectively inSensar AR40e IOL group, and were 0.70±0.19, 0.69±0.23 and 0.67±0.29 in siliconeIOL group. There were no statistically significant differences after operation betweentwo groups regarding mean uncorrected distance visual acuity and meanbest-corrected distance visual acuity. However, those differences exist among thepatients accompanied by diabetes mellitus. The differences of the inflammatory cellsin aqueous humor and the cellular deposits on IOL on the 1st,3rd,7th and 30thpostoperative days between two groups were insignificant while the anterior chamberfibrinous exudate in Sensar AR40e IOL group were much lower than in silicone IOLgroup. The mean astigmatism degree changed little after operation in all patients. 3and 6 months after operation, posterior capsule opacification occurred in 5 and 9 eyesrespectively in Sensar AR40e IOL group while it occurred in 10 and 15 eyes insilicone IOL group. The cases accompanied by diabetes mellitus , posterior capsuleopacification occurred in 3 and 5 eyes implanted with Sensar AR40e IOL 3 and 6months after operation respectively while 9 and 13 eyes had posterior capsuleopacification when implanted with silicone IOL .The position of each IOL was stablein the centric area during the follow ups.Conclusion: 1. The properties of implantation and supporting of the optic centric areaof the Sensar AR40e IOL were very well. The postoperative therapeutic effects of - 5 -第二军医大学 学位论文Sensar AR40e IOL were satisfactory owing to mild aqueous humor inflammations, a lowincidence of posterior capsule opacification and a quick recovery after the operation. 2. For the cataract patients accompanied by diabetes mellitus, thepostoperative therapeutic effects of Sensar AR40e IOL are better than that of siliconeIOL.