The Clinical Research Of Traditional Chinese Medicine Treats The Perimenopausal Syndrome

Perimenopause period is an important physiological stageTn female' s life. It cause by the decay of ovary' s function, which bring on estrogen absence. And many syndromes, such as the hectic fever and sweats the vagina is dry and unsooth and the emotion change appear. Leading to the fact therefrom cardiovascular disease, osteoporosis and senile dementia take place obviously increase, make this kind of woman' s existence quality drop. More and more women enter menopause, the life after menopause extend too . So the treatment and preventing of climacteric syndrome is an important component of global medical hygiene industry.At present, the commonly treatment to perimenopause in modern medical science is hormone replacement therapy (HRT ), which has been verified clinical curative effect, but drug adverse reaction and certain potential carcinogenic risk influence compliance and serviceable range of HRT. There are abundant theories and clinical practical experience to the prevention and cure the syndrome of perimenopause in traditional Chinese medicine. It has the characteristic that diagnosis and treatment based on overall analysis of symptoms and sign and individual treatment.The theory of traditional Chinese medicine is under the guidance of the whole view of Chinese medicine and negative and positive theory. Manage and achieve the goal of improving patient' s symptom and quality of surviving through the dialectical theory. And the herbal toxicity and adverse reaction of traditional Chinese medicine is small, the price is relatively cheap , it has vast development prospects.Through the syndrome measuring scale in menopause, Kupperman measuring scale, survival quality measuring scale, evaluate thedifference of curative effect of climacteric syndrome between traditional Chinese medicine under the dialectical theory and HRT .Through security measuring, the adverse reaction observe forms to compare with the side reaction difference between the two.This test adopts the perspective design plan , collects 60 climacteric patients consistent with internalize standard from climacter special course of study in TCM, from 2002. 10-2005.3. Divided into traditional Chinese medicine group and Western medicine group at random. Traditional Chinese medicine group dialectical divide into deficiency of kidney-YIN and deficiency of kidney-YANG, respectively be gived capsule of gengnianningxinCgengnian NO.1) and oral solutions of bushenyigu(gengnina NO. 3). Western medicine group , the people of already menopaused are gived gengnian NO. 5, the people who aren' t menopausal are gived gengnian NO.6. Compare two groups of curative effect with the side effect after treating for 3 months. Statistical analysis adopts SPSS11.5 counts software package and sets up the database and carries on the statistical analysis of the datas, the main clinical index to the research object is carried on the describing analysis, measurement datas adopt t test, analysis of variance or rank sum test, enumeration datas' group comparison adopt chi square test (including chi-square test of four-fold table, drom *batulate chi square test, fidelity probabilistic method), P=0. 05.The mean age of the case is 49.62±2.907 years old, the menopausal age is 48.03±0.49 years old on average. Among the total, 20.7% is the following culture junior middle school, 48. 3% is the culture of high and middle school, 31. 0% is the culture of above junior college, the course of disease is 34.36+10.60 months on average. Two groups of base-line materials before treating have comparability. Traditional Chinese medicine group and Western medicine group total effective rate after one month of treating is 30. 0% and 28.6% respectively, there is no significance meaning in the difference between two groups; It is 56.6% and 38.4% respectively in the second month after treating, there is significance meaning in the difference between two groups; It is 73.3% and 76.9% respectively in the third month after treating, there is no significance meaning in the difference between two groups.Compare the means of diference between firstvisit and 4 weeks, 8...