Clinical Observation Of Nasal Continuous Positive Airway Pressure(nCPAP) Treatment On Primary Apnea Of Prematurity

Objective To explore the curative effects of nasal continuous positive airway pressure(nCPAP) in primary apnea of prematurity(AOP). Methods In this test study, twenty four premature infants with apnea with the nasal continuous positive airway pressure were chosen as experimental group ,and other twenty one premature infants with apnea without the nasal continuous positive airway pressure as control group.In the two positions,arterial oxygen tension(PaO₂)Arterial carbon dioxide tension(PaCO₂) and arterial oxygen saturation(SaO₂) were determined, and their apnea counts and clinical findings were observed. Results PaO₂ ,SaO₂ in the premature infants with apnea with the nasal continuous positive airway pressure were significantly higher than in the premature infants with apnea without the nasal continuous positive airway pressure(P<0.01) , PaCO₂ in the premature infants with apnea with the nasal continous positive airway pressure were significantly lower than in the premature infants with apnea without the nasal continuous positive airway pressure(P<0.01). In the experimental group , there were 22 cases (91.7%) with seizure reduction and 16 cases (66.7%) with complete cessation , in the control group, there were 14 cases (66.7%)with seizure reduction and 8 cases (38.1%) with complete cessation.There was significant difference between the experimental group and the control group in the efficacy of treatment. Conclusion Oxygenation of primary apnea of prematurity could be improved with the nasal continuous positive airway pressure. The nasal continuous positive airway pressure played an important role in the treatment of primary apnea of prematurity.