Relationship Between Changes Of Endothelin And Cardiovascular Disease In Patients With Kawasaki Disease

Objective: To study the relationship between the level of endothelin in children with Kawasadi Disease(KD) and the cardiovascular disease with KD.Methods:1. Serum endothelin level were detected with radioimmunoassy in 34 patients with KD and 28 healthy children. Comparisons were made between the two groups and between the different clinical course.2. The dimension of dilatation of coronary artery were measured with Doppler echocardiographic techniques. We compared the level of endothelin between the expanded coronary artery group and the unexpanded group.3. To study the changes of CKMB and Cardiac troponin I (CTnI) in 34 patients with KD and to investigate the relationship between the level of endothelin.Results: The endothelin level of 34 children with KD(84.52±...