A Study On Hand Motor Function Area In Patients With Cerebral Infarction

[Objective] To detect the hand motor area of patients with cerebral infarction with fMRI, to evaluate the effectiveness of passive motor to the hand motor center;to evaluate the reformation reconstruction of the brain function.[Subjects and Methods] Forty patients with cerebral infarction diagnosed with conventional MRI were classified into two groups, basal ganglion infarction group (n=25) and cortex infarction groups(n=15).Infarction were classified into three stages according to the clinical standards: acute stage (n=15), subacute stage (n=9), chronic stage (n=16).Block design fMRI was performed with GE 1.5T Twinspeed MR scanner finger lapping task was adopted to activated the motor areas. All patients performed and 24 patients received passive hand motor experiment.SPM99 was used to preprocess the data. Brain functional mapping were superimposed onto T₁WI to localize the activated area. Activated intensity and scope were acquired. Statistical content included followings: â‘ in the acute stage, the activated intensity and scope between bilateral hemisphere were compared in both groups;â‘¡In the acute stage ,the activated intensity and scope of the bilateral hemisphere were compared between two groups;â‘¢In the acute stage, the activated intensity and scope of the bilateral hemisphere were compared between the acute and chronic stage;?In the acute stage, the activated intensity and scope of the bilateral hemisphere were compared between subjective motor and passive motor.[Results]1, In the group of basal ganglion infarction, the healthy hemisphere shows no statistical difference from sick hemisphere in activated intensity and scope. But in thecortex infarction group, the activation intensity and scope in the healthy hemisphere were greater than that in the sick hemisphere. The activation intensity and scope in the healthy hemisphere showed no significant difference between the cortex group and basal ganglion group, but the activation intensity and scope in the sick hemisphere of the basal ganglion infarction group were greater than that in the cortex group.2 > Activated intensity and scope in bilateral SMC had no significant between the acute and chronic basal ganglion infarction group.3> Activated intensity and scope in the sick hemisphere were larger during passive motor than that during subjective motor the activated intensity and scope on the healthy hemisphere had no significant difference between two types of motor tasks.4^The longitudinal observation: the patients with obvious functional recovery of the sick limb, the activation intensity and scope in both hemispheres were strengthened to some extent, activated brain area increased. The activation can be observed in the cerebella.The patients with relatively bad recovery, the activated intensity and scope in sick hemispheres were decreased or vanish. [Conclusion]1 .. Functional MR imaging can detect the damage hand motor, and evaluate the reconstruction of functional area.2 s The functional areas were damaged more seriously in the cortical infarction, and the extent of damage affects the functional recovery. While the motor function was damaged slightly in the basal ganglion group, but in some cases, infarction range covers widely, thus the cortex spinal cord is damaged seriously, and the cortex motor functional area cannot be activated.3> The activated intensity and scope in the sick hemisphere were greater during the passive motor than that during the subjective motor, thus the passivemotor had positive effects on motor recovery of the hemiplegics patients with infarction.4^ In the recovery procedure of motor function in hemiplegics patients with infarction, the brain area surrounding the focus and other area showed functional and structural changes that implied the functional reconstruction.