The Pathological Feature And Analysis Routine Elements Of Drinking Water In Membranous Obstruction Of The Primary Inferior Vena Cava Type Of The Budd-Chiari Syndrome In Heze Area Of Shandong Province

ObjectiveTo study the effect of environment factors in primary inferior vena cava membranous obstruction type of the Budd-Chiari syndrome .Materials and MethodsTo take the biopsys of 8 cases and observed microscopical change by HE stain and CD34 ICH stain. Select 128 cases in 700 cases of inferior vena cava membranous obstruction type of the Budd-Chiari syndrome that we hold all clinic data and investigate their exist circumstance. To examine and analysis routine elements of drinking water.ResultsThe biopsy pathological change is fibrin tissue and thrombus. CD34 ICH stain is negative. The metal elements are normal scope in the drinking water of 128 cases. Content of Iodine in the drinking waterof 128 cases are as follows :98.44% cases are above 150U g/L;27.35% cases are above 150-300 U g/L attributed to high Iodine region;71.09% cases are above 300 u g/L attributed to high Iodine disease region. Content of Fluorine in the drinking water of 128 cases are as follows : 1.56% cases are normal;75% cases are in 1.0-2.0mg/L range attributed to light disease region;23.44% cases are in 2.0-4.0mg/L range attributed to middle disease region.ConclusionPrimary inferior vena cava membranous obstruction type of the Budd-Chiari syndrome pathogenesis is maybe relation to high content of Iodine and Fluorine in drinking water. Iodine and Fluorine are potential toxic factors in the pathogenesis of BCS. KeywordsBudd-Chiari syndrome;Iodine, Fluorine;thrombus;ImmunohistochemistryFluorine in drinking water. Iodine and Fluorine are potential toxic factors in the pathogenesis of BCS.