| Objective To investigate the relation and the mechanisms of cardiovascular disease, type 2 diabetes, tumor and iron status.Methods Fasting morning blood samples from patients (respectively xardiovascular disease 105, type 2 diabetes 105, tumor 105 ) and healthy people (105) were analyzed for serum ferritin (SF), serum iron (SI), total iron-binding capacity(TIBC),transferring saturation(TS),total- superoxide dismutase (T-SOD), glutathione peroxidase (GSH-PX), malon dialehyde (MDA). All the members filled in the dietary survey list.Results 1) The tumor group had the normal weight, the others group all had overweight. 2) In comparison with the heathy people group: significantly increased concentrations of SF and GSH-PX were observed in the cardiovascular disease group;significantly increased concentrations of SF, SI, TS and active of T-SOD, GSH-Px;and significantly decreased concentrations of TIBC were observed in 2 type diabetes group;significantly decreased concentrations of SI, TIBC, TS, and active of T-SOD GSH-PX, significantly increased active of MDA were observed in tumor group (P<0.05). SI,TEBC,TS,T-SOD,MDA in the cardiovascular disease group and SF in tumor group had no significant difference ( P > 0.05 ) . 3) SF significantly correlated to the GSH-PX ( P < 0.01). 4)Nutritional survey showed: most members intook more fat and less vegetable than the reference of dietary guidelines. The cardiovascular disease group intook more potato, meat, fish, shrimp, legumes and less grain than the normal control group (P < 0.01) .Conclusion 1) The changes of iron status was relation to the chronic disease, such as cardiovascular disease, type 2 diabetes, tumor, iron ignant oxidative stress might be the key mechanisms. 2 ) Dietary pattern of most members were not in reason. Dietary pattern of cardiovascular disease group members were singleness, they intook less good protein. We did not find the cardiovascular disease group had intook more food rich in iron.
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