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The Clinical And Experimental Study Of 3D Contrast Enhanced Magnetic Resonance Angiographyin Assessing Peripheral ArteryOcclusive Diseases

Posted on:2007-12-12Degree:MasterType:Thesis
Country:ChinaCandidate:K L ChengFull Text:PDF
GTID:2144360182996724Subject:Medical imaging and nuclear medicine
Abstract/Summary:PDF Full Text Request
With the improvement of the standard of living, the morbidity of theperipheral artery stenosive/occlusive diseases, include the arteriosclerosis, thediabetes related blood vasculitis and the artery embolism, is also increasing.So, 3D CE MRA, as a very important non-intervene diagnosis method for thevascular disease, will bring into play a great effect, although we treat DSA asgold standard at all times. With rapid advangcing of MR, it has taken adirection that 3D CE MRA will replace DSA.We retrospected 103 patients with full information to probe the value ofclinical application of 3D CE MRA for diagnosis peripheral artery occlusivediseases and to assess its accuracy. Taking DSA as gold standard, to compare3D CE MRA with DSA in assessing vascular stenosis/occlusion of animalmodel and to probe if the technique of 3D DCE MRA could replace DSA isthe objective of this experiment. We also simulated the feint during the courseof clinical application to study the reason of the false positive.This wouldprovide the scientific evidences for diagnosing and treating the PAOD.In the clinical study, all the patients with PAOD were convicted by theoperation and all of them underwent 3D CE MRA before it. The examinationswere performed on a 1.5T GE Signa cv/i MR scanner, in combination with areceive-only single coil. And the patient was resupine prone position. Threedimensional spoiled GRE was used. The contrast medium was injected withdual rate, the former injection rate was 3ml/s in the front 25ml, and the latterwas 0.6-0.8ml/s in the last 20ml. The pre-contrast mask sequence was thensubtracted from the post-contrast sequence acquired. Then maximum intensityprojections were calculated from the subtracted data sets. The stenotic degreeof peripheral artery was divided into positive(...
Keywords/Search Tags:Contrast-enhanced MR angiography, peripheral vessels, Arterial, stenosis, animal model
PDF Full Text Request
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