Main Factors Related To Fatty Liver Disease Associating Type Ⅱ Diabetes Mellitus--Case-Control Study

In order to document the main factors related to Fatty Liver Desease(FLD) associating type II diabetes mellitus in the first affiliated hospital of Guangzhou University of Chinese Medicine, we collected clinical information in the Depatment of Disease case room of the first affiliated hospital of Guangzhou University of Chinese Medicine for case-control study, including 63 cases in FLD associating type II diabetes mellitus group(FLDM) and 63 cases in FLD without type II diabetes mellitus group(FLNDM) from January of 2000 to February of 2006. We analyze patterns of Traditional Chinese Medicine(TCM), and find out that Xu pattern(Yinxu pattern and Qixu pattern) in FLDM group are more than FLNDM group (P<0.05), Shi and Xueyu patterns in FLDM group are less than FLNDM group (P<0.05), and the disease locations in spleen in FLDM group are more than FLNDM group (P<0.05). Then we analyze measures(CHOL, TG ApoA, ApoB, HDL-C, LDL-C AST, ALT, GGT, FPG Age) by T Test, Logistic Regression, and Principal Component Analysis. Through T Test, we find out that TG and FPG level in FLDM group is higher than FLNDM group(P<0.05). Through Logistic Regression, we find out that the classification rate equation of risks for FLD associating type II diabetesmellitus is as below: (x₁:FPG, x₂: TG) ,and the correct class ratefor that equation reaches 84.1% (P=.000). Through Principal Component Analysis, we find out that factor 1 (including CHOL, ApoB, LDL-C), factor 2 (including ALT, AST, GGT), factor 2 (including HDL-C, ApoA), factor 4 (including age and low TG) are the principal components for patients with FLD associating type 2 DM, and their cumulative sums of variance explained is 26.202%,49.209%, 63.875% , 76.724% respectively. So weconclude that in the first affiliated hospital of Guangzhou University of Chinese Medicine from January of 2000 to February of 2006, the main patterns of TCM are more Xu pattern (Yinxu and Qixu ), less Shi and Xueyu patterns, and the disease location is in spleen for patients with FLD associating type II DM;The independent dangerous factors for patients with FLD associating type II DM are high glucose and high TG, and the principal components are cholesteroK liver function and fast plasma glucose% content of protein in lipoprotein -. age and low TG in sequence.