The Experimental Study Of Reconstruction Of Mandibular Defects By Internal Curvilinear Distractors

Distraction osteogenesis(DO) was first reported by Codivilla--an Italian scholar in 1905, and then systematically studied by Ilizarov, and a set of laws for clinical practice was worked out. In 1973, Snyder firstly brought Ilizarov's laws to the animal experiment of reconstruction of mandibular defect. Then McCarthy firstly studied the clinical application of DO in the field of oral and maxillofacial surgery. So far, DO has been used very common in maxillofacial surgery. However, most of the studies have focused on straight DO presently, only linear bone defects of small scales could be treated by them, such as defects in the mandibular body. However, many of the defects of jaw bones in the field of oral and maxillofacial surgery are far more complicated, few of them are linear ones. They are difficult to be reconstructed. So, studies for curvilinear distraction osteogenesis are of great necessity. Though some curvilinear distractors have been invented, they were usually external types. However, external distractors could cause many complications in the process of mechanical traction. Internal curvilinear distraction osteogenesis is being studied now, and some kinds of internal curvilinear distractors have been reported. However, they were not so good as to be used clinically.This study brought forward a series of internal curvilinear distractors, and carried out ex-vivo and in-vivo experiments to test the feasibility of reconstruction of mandibular angle defects by internal curvilinear distraction osteogenesis, and to investigate the probability and regularity of the new...