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Study On Brain Damage And Immunological Inflammation Factors In The DNS Model Of Rats After Acute Carbon Monoxide Poisoning

Posted on:2007-03-24Degree:MasterType:Thesis
Country:ChinaCandidate:T Z ZhaoFull Text:PDF
GTID:2144360185470899Subject:Aviation, aerospace and maritime medicine
Abstract/Summary:PDF Full Text Request
Carbon monoxide (CO) poisoning is a venenation with high incidence rate and mortality rate. It can be seen in the situation of fire disaster, excessive revelation of motors' end gas, and accidents happened in industry or in the use of stove for heating, cooling and bathing in our daily life. Suicide with CO also can be heard sometime. In the patients of CO poisoning, 3%-30% will develop the delayed neuropsychologic sequelae (DNS ) which is characterized by dementia, psychiatric symptoms and extrapyramidal symptoms after a period of latent phase (days to weeks). Yet , the pathogenesis of DNS has not been elucidated.The basic function of immune system is to react to the substance of antigen. With the immunological inflammation reaction activated by the immunocell, body can clean up the substance of antigen. Recently , a lot of reports about the character of central nervous system (CNS) have shown that...
Keywords/Search Tags:Morris water maze, acuter carbon monoxide poisoning, interleukin-1β(IL- 1β), γ- interferon (γ- IFN), immunological inflammation, microglia, rat, hippocampus, cortex, histopathology, immunohistochemistry
PDF Full Text Request
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