The Echocardiographic Evaluation And Study On The Left Ventricle Filling And Hemodynamics In Chronic Obstructive Pulmonary Disease

Objective 1. To study the blood flow velocity variations across the four cardiac valves during spontaneous respiration and contrast it in normal people and chronic obstructive pulmonary disease ( COPD ) by echocardiography. 2. To elucidate the mechanism and clinical significance of nature respiration on left ventricle filling and hemodynamics. 3. To provide evidence for verify the new hypothesis of the mechanism of respiration effects on hemodynamics.Methods Pulsed-wave Doppler spectra across all four cardiac valves were recorded by Acuson Sequoia 512 in 21 COPD patients and 39 normal control subjects, transducer 3V2c, frequency range 2.5 ~ 4.0MHz. Electrocardiogram and respiratory tracing by a nasal thermistor were recorded simultaneously. The blood flow velocities across all the cardiac valves were measured at the onset of inspiration and expiration, then the velocities were...