Effect Of ERK Signal Transduction On The Cell Proliferation Of Human Retinal Pigment Epithelium Stimulated By Hypoxia.

Retinal pigment epithelium (RPE)cells are the monolayer cells located between the retinal photoreceptor cells and chorioid. The normal RPE cells are not proliferation and migration , but in the pathological conditions they can transmigrat ,secrete, proliferate and transformat. These potencies are related to many ophthamological diseases, such as proliferative vitreoretinopathy , the retinal extensive proliferation of new blood vessels , age-related macular degeneration .Vision loss in the pathological conditions suffers the patients a lot.Current therapies such as panretinal...