The Primary Study Of Alginate/β-Tricalcium Phosphate Hybrid Scaffolds For Bone Tissue Engineering

Every year, millions of surgical procedures are performed that require tissue or organ substitutes to repair or replace damaged or diseased organs or tissues. Conventional approaches include: autografting, allografting and man-made materials and device, while all these therapies have had significant medical impact, including the additional surgical costs for the harvesting procedure, and infection and pain at the harvesting site and shortages in donor availability and so on. This limitation has driven the development of the tissue engineering field. Tissue Engineering, developed in later 1980s, is a multidisciplinary field that applies the principles of biology and engineering to develop tissue substitutes to restore, maintain, or improve the function of diseased or damaged human tissues.The quick development and breakthrough of critical techniques are also displayed in bone tissue engineering. It is essential to select appropriate seed cells and scaffolds in bone tissue engineering. BMSCs are considered as ideal seed cells due to their multi-directional differentiation...