Background: Some researches have shown that the posture doesn't influence the central venous pressure (CVP) in the healthy, but the results in critically ill patients are controversial. The mechanical ventilation (MV) increases CVP. In present, the patients have to be adjusted to supine flat and detaching from the ventilator at the time of measurement. In order to simplify the procedure and reduce the interference to the patients, we designed the research.Objective: To investigate the effect of posture and mechanical ventilation on CVP in critically ill patients.Methods: In a prospective self-controlled research, critically ill patients undergoing mechanical ventilation were enrolled. Heart rate (HR), mean arterial pressure (MAP), CVP, oxygen saturation of pulse (SpO2) and Riker's Sedation-Agitation Score (SAS) were measured respectively with a backrest elevation of 30° or with a supine flat position at different MV conditions. At first, the parameters were measured on both postures when detaching ventilator. Then, the parameters were measured on both postures...
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