Effects Of Late Reperfusion Therapy On Left Ventricular Function And Prognosis For Patients With Chronic Total Occlusion

Objective: The purpose of this study was to compare the clinical character, coronary artery lesion, the left ventricular function and the occurrence of the major adverse cardiac event(MACE) of the chronic total occlusion(CTO) patients who received percutaneous coronary intervention with those who only received medication by coronary angiography, ultrasonic cardiogram(UCG) and equilibrium radionuclide angiography (ERNA) to elucidate the effects of late reperfusion on patients with CTO and the perhaps mechanisms.Methods: 81 patients (66 male and 15 female, average age was 62.41±6.9 years old) with chronic total occlusion were enrolled. Depending on whether the occluded coronary artery was reopened, the patients were divided into PCI group(n=37) and Medication group(n=44). Inclusion criteria included both complete occlusions(Thrombolysis In Myocardial Infarction [TIMI] flow grade 0), where no anterograde filling beyond the lesion was visible, and functional occlusions(TIMI flow grade 1), where a faint, late anterograde flow with incomplete opacification of the distal vessel in the absence of a discernible lumen channel. Patients with angina or inducible ischemia by...