Study Of Antibacterial Effect On Berberine Combineded With Ceftazidime To The Extended-spectrum β-lactamases-producing E.coli Strains

Alone with the extensive usage of various antibiotics, the drug resistance problem become more and more outstanding, threatenning seriously public healthily. It has become a serious problem that the people must face, and the ESBLs-producing E. coli strains make this problem more serious. The traditional Chines medicine composition is complicated, which can affect metabolism in several 1 ink of the bacterium metabolism .The modern pharmacology has proved that many traditional Chines medicine has a better antibacterial effect. The traditional Chines medicine combined with western medicine for clinic can produce better function than alone medicine, showing that the reasonable antibacterial effect superior.In recent years, it is widely accepted that the wide antibacterial spectrum of the berberine (Ber)and can eliminate plasmids of E. coli. The Ber resist to various bacterium, but is less towards the research that the ESBLs-producing E. coli. Ceftazidime (CAZ) that is the third generation typs the antibacterial spectrum is wide, the function is strong and stable to various...