| Polybrominated diphenyl ethers (PBDEs) are a kind of fire(flame) retardant chemicals. PBDEs are composed of two six homocyclic rings carrying halogen (bromine). Because the carbolic number and position replaced by bromine in two benzene rings are different, 209 homologs are formed altogether. Some of those have been shown to be mainly for commercial use, while deca-BDE is the most widely used, accounting for 75% of the total production quantity for PBDEs; in the world.After studied related the harm of low bromine PBDEs to the humanity health, it discovered that four bromines (tetra-), five bromines (penta-), and six bromines (hexa-) PBDEs can persistence exist in some target organs (liver, the spleen, kidney, adrenal cortex, ovary, lung and brain)and accumulation,and harm to these organ functions. The animal experimentation discovered that PBDEs (tetra-BDE, penta-BDE, hexa-BDE, oca-BDE) disturbs to the thyroxine metabohsm and affect the nerve growth, specially in perinatal period to contact PBDEs was able to hinder the nerve and the skeleton growth, causes the nervous system and the capacity permanent influence; It also can harm the hormone system, possibly by hindrancing the endocrine hormone adjustment on the estrin channel ,and causes the growth and development retardation, the puberty hysteresis as well as the immunity system produces bad affects. Also some people discovered that PBDE-47 (tetra-BDE) can stimulate in the gene to reorganize, moreover also has the obvious relevance in statistics.It explained PBDE-47 may initiation cancer by the gene mutation material through the way of the non- induction. Along with the low bromine PBDEs harm clarification, on international it has reduced amount of use, even to ban.
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