Study On The Circadian Rhythm Adjusting By Garlic Cream Pasting On CV8

Objective: There are too many factors that can cause circadian rhythm disorder, such as work in shifts and a military action, which will do harm to men's body and lead to descending of efficiency and fighting capability. The method that can be widely used to adjust circadian rhythm is very rare, and the effect is not very confirmed. In our experiment, we observed the effect on adjusting the circadian rhythm by garlic cream pasting on CV8 caused by sleep deprivation, we did want to approach the mechanism and provide experimental basis for preparing an external application agent to adjust circadian rhythm.Methods: Twenty healthy young men from the South Medical University were divided randomly into three groups, normal group(A) including six, sleep deprivation group(B) and treated group(C) including seven each other. Subjects in group B and C were taken 48 hours' sleep deprivation, garlic cream were pasted on CV8 of people in group C at the beginning of sleep deprivation, and those in group A were kept staying in a normal daily state whithout any interference. The temperature, blood pressue and heart rate of the three groups were observed at four different times, which was called Zi shi, Wushi, Mao shi and You shi in TCM respectively. The saliva level of cortisol, the urine level of amylase, the blood level of IgA, noradrenaline and serotonin were detected at these different times too. At last the data were analysed in cosine method and cosine curve were drawed according the data, then we would know whether there was daily rhythmicity in these target.