Studies On Nasal Delivery System Of Cangerzisan Thermosensitive Gel

Nasal delivery system is a traditional Chinese Medicine (TMC) which is applied to nasal by nasal mucous membrane. The effect of the Nasal delivery system is part or whole. Such a preparation has a long history in our country. It can treat not only nasal disease such as rhinitis or nasal abscess but also some general disease; therefore it has been more and more popular. Via the sample of a classical TCM prescription which is mainly used to the treatment of nasal disease, this project is going to study the ingredient, distill technology, dosage form, curative effects, and to explore the preparation of the TCM thermosensitive gel in order to develop the nasal delivery system of the TCM.The classical TCM prescription is composed of four kind of herb. Based on the establishment of the evaluation method, the paper systematically studied the process conditions, formulation design, quality standard and stability of preparation in order to find a better dosage form for the prescription.Establishment of evaluation indexes and methods is the key to evaluate reasonable method of preparation and the important aspect of quality evaluation TCM Complex Dosage.In the light of nature of ingredient, the paper set up UV method of mixture of the volatile oils.HPLC method of imperatorin to select process condition of preparation technology in order to determine effective components.For guaranteeing the effectiveness of TCM Preparation, that valid compositions in CMM are leached fully is the primary. In the light of each herb's pharmacological functions in the prescription, considering reference and...