Application Evaluation Of Lung Ventilation And Perfusion Imaging Technique In Diagnosis Pulmonary Embolism

Experiment 1Objective To assess contrast study of lung ventilation-perfusion imaging and pulmonary angiography in diagnosis pulmonary embolism (PE) .Methods Sixty patients with clinically suspected pulmonary embolism were studied , male∶female = 30∶30, mean age was (43.5±11.3) years. All patients underwent both radionuclide ventilation -perfusion imaging and pulmonary angiography.Results Of the 60 patients , 44 with lobe ,multiple segment or multiple subsegment perfusion defects and normal or nearly normal ventilation images were reported as PE. 43 of them were confirmed to be PE by pulmonary angiography , 2 patients were not confirmed. 15 of 60 were confirmed to be non-PE by pulmonary angiography,1 patients were confirmed to be with PE. The sensitivity ,specificity of diagnosis of PE by ventilation and perfusion imaging was 97.7% , 83.3% respectively.Conclusion Pulmonary perfusion and ventilation scan is no invasive ,the most valuable method in the diagnosis of pulmonary embolism.Experiment 2Objective To assess contrast study of lung ventilation-perfusion imaging and CT pulmonary angiography in the diagnosis of pulmonary embolismMethods During August 03 ~06 December, clinical pulmonary angiography in the diagnosis of 93 patients with PE. 60 males, 33 females, mean age (43.5±11.3) years. In accordance with the Chinese Medical Association of Respiratory Diseases《pulmonary thrombo-embolism diagnosis and treatment guidelines (draft)》set the standard classification , the patients were divided into large, PE major area (group A) and un-large (excluding large area) PE (group B). All patients were detected with CTPA and pulmonary perfusion and ventilation scan .Image analysis by two experienced physicians. Statistical Methods on x2 test, P<0.05 with statistically significant.Results In 93 patients of PE, pulmonary perfusion and ventilation scan in 86 cases were positive, the total detection rate of 92.47%. CTPA positive in 83 cases, the total detection rate of 89.25%.Both detection without statistically significan(tx2=0.58,P>0.05). A: pulmonary perfusion and ventilation scan in patients with positive 36 cases, the detection rate of 85.71%; CTPA positive patients in 42 cases, The detection rate of 100%, CTPA detection rate significantly higher than pulmonary perfusion and ventilation scan (x2=4.49. P <0.05).B: pulmonary perfusion and ventilation scan were positive in 50 cases, the detection rate of 98.03%;CTPA positive patients in 41 cases, The detection rate of 80.39%, pulmonary perfusion and ventilation scan was significantly higher than the CTPA (x2=8.25. P <0.05).Conclusion Central PE in patients with superior detection rate CTPA than pulmonary perfusion and ventilation scan; PE in patients with peripheral detection rate perfusion and ventilation scan is superior to CTPA. Both have advantages and disadvantages, we should be both diagnostic techniques complementary strengths, This is necessary for the clinical treatment more accurate and effective messages. Conclusion pulmonary perfusion and ventilation scan is the clinical diagnosis of pulmonary embolism of the most valuable non-invasive diagnostic methods, Pulmonary embolism can be used as first-line diagnostic tool that is safe, noninvasive, simple and economic advantages.