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Comparison Of Percutaneous Coronary Intervention Characteristics In Patients With Or Without Type 2 Diabetes Mellitus

Posted on:2008-04-26Degree:MasterType:Thesis
Country:ChinaCandidate:S Q KouFull Text:PDF
GTID:2144360215489224Subject:Department of Cardiology
Abstract/Summary:PDF Full Text Request
ObjectiveTo compare the clinical characteristics (general information,past history, history of smoke and angina type etc) and features ofpercutaneous coronary intervention (PCI) (information ofintervention, situation of lesion, information of blood stream, typeof lesion and information of stent, etc) in a large series of diabeticand non-diabetic patients with coronary heart disease (CHD)undergoing PCI. Meanwhile, to evaluate the proportionalcharacteristic of patients with CHD complicated diabetes,characteristic of coronary artery lesion and the influence of diabetesmellitus on PCI.Methods1. 1441 consecutive patients underwent PCI from January toDecember 2006 in Tianjin Chest Hospital were analyzedretrospectively. All patients were divided into two groups, diabetesmellitus group and non-diabetes mellitus group. Related clinicalinformation of patients was collected.2. Data related PCI were collected. The parameters includedpositions, characteristics and types of lesions, information of stentsand complications, etc.3. All these parameters were compared between the twogropes by using SPSS10.0. Data showed as(?)±s. P<0.05 means statistical significance.Results1. Two hundred and twenty-three patients (15.5%)complicated with diabetes. Female patients, complicatedhypertension and hyperlipidaemia were more prevalent in patientswith diabetes than those in group of non-diabetics (P<0.05).2. Type C lesion was more prevalent in patients with diabetesthan those without diabetes (38.3% vs 19.7%; P=0.022).3. The numbers of managed lesion, numbers of stents anddrug-eluting stents in diabetic group were more than that innon-diabetic group (1.42±0.62 vs 1.28±0.51, 1.63±0.84 vs 1.47±0.69, 77.1% vs 71.5%, P<0.05). The average stent diameter wassmaller in diabetic group than that in non-diabetic group [(3.00±0.42)mm vs (3.06±0.43)mm, P<0.05]. The other clinicalcharacteristics and PCI procedure had no significant differencesbetween two groups.Conclusions1. There were higher prevalence of hypertension andhyperlipidaemia in patients with coronary artery diseasecomplicated diabetes.2. The coronary artery lesions were more serious in patientswith diabetes mellitus.3. During management of coronary lesions, more lesions hadto be stented in patient complicated diabetes, so that more stentsand smaller diameter of stent were needed.4. Compared with non-diabetic patients, the percent of PCI in diabetic patients was lower.
Keywords/Search Tags:Diabetes mellitus, coronary heart disease, coronary artery, percutaneous coronary intervention
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