The Study Of Cardiac Remodeling And Changes Of Left Ventricle's Function And Haemodynamics After Total Correction Of Tetralogy Of Fallot

【Objective】To study cardiac remodeling and changes of left ventricle'sfunction haemodynamics combination with color ECG after totalcorrectionof tetralogy of fallot.【Methods】We reviewed 62 patients(female 35, male37) who underwent total correction of tetralogy of fallot under generalanesthesia and extracorporeal circulation between February 2004 and August2006. These patients are between 10 months and 15 years old, average age7.6 years old and body weights are 4.5～61kg, average weight 22.5kg. Amongthese patients, there are 9 patients less than 3 years old., 12 Leftventricular end-diastolic volume(LVEDV)≥25ml/m~2,＜30ml/m~2(average:29.36±6.82 ml/m~2) and 7 patients 1.1≤McGoon＜1.5(average:1.3). Determinethe inside diameters of aorta, main pulmonary artery, left atrium, rightatrium, right ventricular outflow tract, and left ventricularend-diastolic dimension[LVEDD], left ventricular end-systolicdimension[LVESD]before operation, discharge and postoperative 3 months respectively. Then making use of Cube formula, automatic calculate LVEDV,LVESV, LAEDV, LVEF, LAEF, LVEF, LAEF, LVFS, CO and CI. The data was comparedthrough paired t-test.【Results】Compared with preoperation, after totalcorrection of tetralogy of fallot, the blood flow rate of main pulmonaryartery slowed down obviously (p＜0.05), the diameter of LVEDD increasedgreatly (p＜0.05). Compared with discharge, postoperative 3 months, theinside diameters of left atrium, main pulmonary artery, the blood flow rateof aorta, LVEDD and LVFS increased (p＜0.05). Compared with preoperation,after operation, the inside diameters of left atrium, main pulmonary artery,LVEDD and LVESV increased obviously (p＜0.01), moreover, right atrium,LVESD, LVEDV and right ventricular outflow tract increased (p＜0.05). Theblood flow rate of aorta was obviously faster than preoperation (p＜0.01),the diameter of aortic root reduced obviously (p＜0.01) and the blood flowrate of main pulmonary artery slowed down obviously compared withpreoperation (p＜0.01). Moreover, LVSV, CO and CI increased obviously (p＜0.05), but the change of LVEF was not obvious during three periods (p＞0.05).【Conclusions】There is an obvious cardiac remodeling after totalcorrection of teralogy of fallot. Not only volume load of right ventricularwas relieved but also left ventricular contractile function was improved.