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The Impatient Alcoholism Adjusts To Control Mechanism To The Brain Slice And The Influence And Gegen Root Vegetable Of The Ammonia Activity

Posted on:2008-04-20Degree:MasterType:Thesis
Country:ChinaCandidate:J P ZhuFull Text:PDF
GTID:2144360215965217Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
Objective: The impatient alcoholism is the emergency call clinical famili ar disease, to the human body endanger biggest. Because the sufferer obeys sex to differ, bringing treatment a not small difficulty. The modern res earch confirms impatient alcoholism and theβ-slice inside the human bod y, brain slice have a close relation, to the doctor treatment in the impa tient alcoholism research is as well on the up. The research expresses im patient alcoholism opportune moment body's ising placed in should arouse appearance, mightiness of should arouse to cause the storage is in hang t he body of inside source slice (OLS) releases in great quantities, the me tabolism outcome acetaldehyde of alcohol synthesizes OLS with dopamine in the body, another alcohol metabolizes of some solidify an outcome to als o have slice kind function, these slice material direct or indirect funct ion in inside brain the slice be subjected to a body but cause axis and b reathe, circulate to repress is an impatient alcoholism of main mechanism. Gegen's useding for to solve wine has already had long history, the appli cation study is subjected to people's concern increasingly in the aspects of curing alcoholism now, however the solution wine's mechanism of the g egen hasn't made to know up to now. The thesis topic passes observation ge gen a vegetable model to the impatient lcoholism domestic rabbit of insid e source slice brain,β-slice inside content and brain slice of declin e to solve the ammonia influence of the activity, analytical brain slice,β-slice inside and ammonia of the alcohol density relativity, unders tanding gegen vegetable cure impatient alcoholism whether ability prepare the brain slice content and raise ammonia the activity, understand a ge gen whether vegetable have an exaltation ammonia the slice to solve an ab ility to the brain slice or not, inquiry into a gegen a vegetable to cure the function mechanism of impatient alcoholism thus, end for develop Chi nese herbal medicine gegen and it withdraws thing as to solve a wine to p rovide experiment foundation.Methods: Pass examination domestic rabbit alcohol in front and back blood brain slice ,β-EP content, the ammonia activity and the alcohol density, observe domestic rabbit to drink the wine difference between now and bef ore stage brain slice andβ-EP, the brain slice and ammonia activity, brain slice and of the alcohol density influence. The blood brain slice andβ-EP release level after understanding alcohol incitement domestic Tab bit and and time relativity, understand ammonia to inside slice the decli ne a solution function, whether gegen vegetable has exaltation to solve a n ability to the brain slice or not, inquiry into a gegen a vegetable to cure an impatient icoholism function a mechanism thus. Pass a clinical col lections case also, adopt to check against an experiment design random, is divided into impatient alcoholism sufferer random gegen plain set(treat ment set) and the naluotong set(matched control), the observation combine s verification gegen vegetable's treatment to impatient alcoholism result.Results: All covariance datas all adopt SPSS covariance a software packag e to carry on statisticsing analysis. Animal experiment research enunciati on andβ-EP of alcohol density and brain slice release level and have r elativity with time, gegen plain set and the naluotong set comparison urg es to come to time top to have no obvious difference at domestic rabbit(P<0.05), But have already shown difference in lowering the brain slice an dβ-EP level(P>0.05), This probably still has with gegen vegetable oth er regulate a mechanism relevant. The clinical research also expresses a g egen vegetable of urging and coming to time and naluotong have no obvious difference. The clinical trial didn't discover obvious toxicity and bad r eaction.Conclusion: Pass an above research, confirm an impatient Icoholism condit ion more heavy, the brain slice level is more high, the ammonia activity is more low. The gegent vegetable can lower impatient alcoholism domestic rabbit brain slice level, and raise the ammonia live function, rise thus quickly a purpose of coming to the wine. Developing the gegen's coming to a wine product can for the impatient alcoholism sufferer provide quickly, safe and valid solution wine Chinese herbal medicine.
Keywords/Search Tags:Impatient alcoholism, Poisoned mechanism, The gegen is plain
PDF Full Text Request
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