The Analysis Of Relativity Factors To Hypoxemia After CABG

Objective As the coming of the aging society and the exaltation of living level, the rate of coronary atherosclerotic heart disease (CAHD) is rising year by year. As the main treatment way for CAHD, coronary artery bypass grafting (CABG) has being developed extensively in a lot of hospitals. With the improvement of operation technique, more and more patients of eld serious CAHD or having illness of other organs who elected GABG This made the incidence of hypoxemia after CABG increased and became hot topic in the department of cardiovascular surgery. Hypoxemia after CABG can make the heart rate fast, the blood pressure high, the heart overburdened and reduces the tissues taking oxygenation. These often last several days or even longer after operation. And these cause complication of cardiovascular, brain or the surgical operation slices. And there are further results such as delaying recovery, staying in hospital for extensional time and increasing expense. Inaccuracy treatments for seriously hypoxemia often endanger the sufferer's life safety and influence directly the sufferer's survival and prognosis. The analysis of the related factors of hypoxemia after CABG can provide a theories for clinical treatment and prevention hypoxemia and decrease the occurrence of hypoxemia after CABG with this.Materials and Methods Collected 135 cases undergoing CABG in Cardiovascular Surgery Department of the First Affiliated Hospital of Zhengzhou University from January, 2003 to December, 2005. Among them, male: 100, female: 35; average age: 60.11±8.81; average weight: 69.91±9.97kg. There were 77 cases that had circulation coronary artery bypass grafting (CCABG), 58 cases that had off-pump coronary artery bypass grafting (OPCABG). The number of graft was from 1 to 5. The average time of aorta breaking to flow is 80.45min; cardiopulmonary bypass (CPB) is 121.56min. Recorded P_aO₂ and analyzed the occurrence rate of hypoxemia in different factors such as time rule, sex, weight, smoking, high blood pressure, diabetes, heart function, the number of pathological changes of coronary, the time of CPB, the time of aorta breaking to flow and the time of operation, analyzed the occurrence rate of CCABG and OPCABG. by SPSS11.0. The examination standard wasα=0.05.Results There were 44 cases (32.59%) in 135 to erupt hypoxemia. The emergence of hypoxemia in the first day after CABG was the most frequently and there was not obviously difference between before extubation and after it. Compared other factors of the occurrence of hypoxemia: the incidence in patients older than 60 years was obviously higher than those younger than 60 years, P<0.05; the incidence whose weight was more than 70 kg or equal was obviously higher than those weight was less than 70 kg, P<0.05; the incidence of smoking was obviously higher than non-smoking, P<0.05; the incidence after OPCABG was obviously lower than after CCABG, P<0.05; the incidence of CPB lasting for longer than 121.56 minutes was obviously higher than those shorter than 121.56 minutes P<0.05. And the time of aorta breaking to flow longer than 80.45 minutes caused higher incidence compared to shorter than 80.45 minutes P<0.05. Operation time, high blood pressure, the number of illness coronary artery and heart function didn't show obviously relativity with hypoxemia after CABG. And diabetes, cardiac aneurysm didn't neither. The possibility was because of the observation number was little. This needs a further research. In this investigation, the incidence of hypoxemia had obvious difference in sex. Maybe, it was because the female case was small and it needs to be confirmed.Conclusion 1. The incidence of hypoxemia after CABG was obviously lower than after CCABG. 2. The time of CPB and aorta breaking to flow were the important factors that affected the incidence of hypoxemia after CABG.3. Age, obesity, smoking showed obviously relativity with hypoxemia after CABG.4. Operation time, high blood pressure, the number of illness coronary artery and heart function didn't show obviously relativity with hypoxemia after CABG.5. the influences of diabetes and cardiac to hypoxemia after CABG needs to be researched in the future. Whether the incidence of hypoxemia after CABG has sex differences or not needs to be confirmed.