The Clinical Application Of SPECT/CT In Breast Tumor Imaging

Objective:To study the clinical value of the combined SPECT and CT in breast tumor imaging and evaluate axillary lymph node metastasis and bone metastasis.Methods::Total 80 female patients with breast masses in our hospital were examined by SPECT/CT detection;Every patients underwent breast scanning using Technetium-99m-sestamibi⁹⁹Tc^m-MIBI)and SPECT/CT.The position patieng of breast imaging with ⁹⁹Tc^m-MIBI underwent ⁹⁹Tc-methylene diphosphonate(MDP)whole bone scanning and SPECT/CT bone scan.The scintigraphy results were analysed.compares with the pathology results.Results:51 of 80 patients were breast cancer,29 of 80 patients were benign breast masses. The sensitivity of fusion image was higher than planar image in diagnose of breast cancer were (88.2%vs82.4%,P＜0.05).The specificity and accuracy of fusion image were93.1%vs 90% respectively,the positive findings in combined SPECT/CT were more than those of planer imaing(79.3%vs 81.3%)。.These Sensitivity(77.2%vs81.8%)and specificity(86.2%vs89.7) of fusion imaging and planar imaging respectively in detecting axillary lymph node metastasis.18 of 45 patients were positive in whole body bone scan,16 of 18 patients were diagnosed for bone metastasis.Conclusion:Combined SPECT and CT has high Sensitivity and specificity in detecting breast cancer and axillary lymph node metastasis.The specificity in combined SPECT/CT bone scan were significantly more than those of planer imaing.