The Hemodynamic Influence By High Frequency Oscillation Ventilation (HFOV) On Adult Patients Undergoing Intravenous And Combined Spinal & Epidural Anesthesia (CSEA)

Objectives To compare the hemodynamic influence by high-frequency oscillation ventilation(HFOV) with conventional mechanical ventilation (CMV) approach on adult patients undergoing intravenous and combined spinal epidural anesthesia (CSEA).Methods It is a randomized crossover and controlled study. Twenty patients aged 30 to 70 years old with ASAⅠ—Ⅱundergoing elective colectomy or rectectomy were randomly divided into two ventilated groups: CMV/HFOV (at first ventilation on CMV mode then on HFOV mode and HFOV/CMV (at first ventilation on HFOV mode then on CMV mode). The CMV (n=18) is the control group and the HFOV (n=18) is the study group. Hemodynamic parameters and Arterial Blood Gas analysis were taken after 15 minutes on CMV or HFOV.Rsults To compare with CMV, the pulmonary circulation parameters(MPAP, PVRI and CVP) were significantly increased (P＜0.05) on HFOV mode. There was no significant difference between the two groups(P＞0.05) on hemodynamic parameters (HR, PAOP, CI, MAP, SVRI) and Arterial Blood Gas analysis (pH, PaO₂, PaCO₂, BE).Conclusion It is concluded that there is no adverse influence on hemodynamic parameters on HFOV mode compared with CMV on adult patients undergoing integrated intravenous and CSEA.