The Clinical Value Of Sentinel Lymph Node Detection With Radionuclide In Early Cervical Cancer

Objective: To investigate the feasibility of sentinel lymph node (SLN) detection with radionuclide early cervical cancer patients. Methods: Between December 2005 and December 2006, a total of 16 patients with cervical cancer international federation of obstetrics and gynecology (FIGO) 2000 from stage CINIII to IIb were eligible for the study. The day before surgery, the 99mTc-dextran (99m Tc-DX) was injected into the cervix at 12°,4°and 8°.Before the operation followed by preoperative lymphoscintigraphy to detect the SLNs.During the operation, SLNs were identified from dissected LN byγ-counter.The samples of SLNs and non-SLNs (NSLN) were recorded separately and compared with the final pathology results. Results: The sensitivity,specificity,and the accuracy of the SLN detecting to predict the metastasis of the pelvic lymph node were100%,99.2%,100%,respectively.Condusions: SLNs can successfully predict the lymphatic metastasis in patients with cervical cancer.The clinical validity of this technique should be further evaluated.