Dynamic Contrast-enhanced Magnetic Resonance Imaging In Breast Lesions Diagnosis Of Value

Objective: Discuss the value of Contrast-enhanced MRI in the diagnosis of in breast lesions. Method: 40 cases of breast disease patients underwent MRI plain scanning and dynamic scanning. Among the total, 33 cases were benign lesions, 24 were malignant lesions underwent postoperative pathology or biopsy confirmed, then analysis the enhancement of morphological characteristics, measure the dynamic parameters, including time-signal intensity curve type, time to peak and early enhanced rate, and statistical analysis. Results: The majority of lesions can not be detected by MRI scanning, while combining of morphological characteristics, the sensitivity is 75%, the specificity is 69.7% and the accuracy is 71.9% for detection of breast cancer. Most types of benign lesions were round or lobulated, Edge Finishing clear boundary, and eccentric strengthening enhance uniformity; Malignant lesions are more irregular shape or burr, obscure border, to strengthen and enhance mental uneven. The difference of the time-signal intensity curve between benign and malignant lesions are statistically significant (P< 0.001). Diagnostic sensitivity is 91.7%, specificity is 87.9% and accuracy is 89.5%. The difference of early peak time rate increasing between benign and malignant lesions was statistically significant(U-value were 20.50,107.0, P<0.001), the former sensitivity is 87.5% and specificity is 87.9%, accuracy is 87.7%; the latter diagnostic sensitivity is75.0% and specificity is 84.8%, accuracy is 80.7%. Combining of dynamic scanning, the sensitivity is 95. 8%, the specificity is 87.9% and the accuracy is 91.2% for detection of breast cancer.Conclusions: Time-signal intensity curve, the peak time and the rate of increase have higher sensitivity and specificity in early identification of benign and malignant breast disease. with enhanced characteristics, the most benign and malignant lesions were given diagnosis,which had important value in the diagnosis and differential diagnosis in the benign and malignant lesions.