| Research background and ObjectiveAlthough the domestic and foreign research have demonstrated that the perinatal stage deepvein thrombus formation rate is relatively rare, once the progress is the pulmonary embolism, themotality rate is extremely high. Along with the living standard enhancement, in front of the deepvein thrombus and the thrombus the condition disease incidence rate has assumed the tendencywhich advances gradually. At present also does not have in front of the special thrombus in frontof the condition in particular perinatal stage thrombus the condition forecast target, the majorpart research is the review investigation, still could not establish the research target and the PPTScausally related. In front of the formerly thrombus and the thrombus the condition diagnosistechnology often is disease develops certain stage only then to have the high diagnosis rate, thediagnosis method usually is the intrusional inspection, the expense soaring, the existence highrisk, the patient complies is low, because but the colored Doppler supersonic inspection it notcreates, conveniently, the real-time dynamic check, the duplication good, the diagnosiscoincidence rate high merit, had the gradually substitution to have creates the inspectiontendency, in on clinical receives day by day takes. This research use colored Doppler supersonictime or inspects the health full-term easy childbirth pregnant woman many times and has thehigh-risk factor full-term pregnant woman, post-natal 2-5 day, the post-natal 42-45 day pregnant woman double lower limb deep vein, whether there is observes the thrombus and theconcealment thrombus, and surveys the part double lower limb deep vein the inside diameter andthe blood stream change, simultaneously dynamic monitor hematology target PLT, HGB, HCT,D-D, TT, APTT, PT, FbgC, the observation perinatal stage healthy pregnant woman and in frontof the high-risk pregnant woman thrombus the condition lower limb deep vein inside diameterand the blood stream change rule as well as each item of blood target change rule, discusses infront of initially the perinatal stage high-risk pregnant woman thrombus the condition diagnosismethod. The condition diagnosis and the treatment provides certain assistance basis for theperinatal stage high-risk pregnant woman thrombus.MethodsWe select the full-term pregnant woman who labour in our hospital with the high-risk factorsince February, 2005 to February, 2006 128 cases to take experimental group A1, the healthyfull-term pregnant woman 61 examples to take same time experimental group A2, the selectionsame time has the above high-risk factor post-natal 2-5 day parturient woman 212 examples totake experimental group B1, the post-natal 2-5 day in health full-term easy childbirth parturientwoman 77 examples took experimental group B2, has the thrombus to form the high-risk factorthe post-natal 42-45 day parturient woman 137 examples to take experimental group C1, Thepost-natal 42-45 day in health full-term easy childbirth parturient woman 49 examples tookexperimental group C2, and respectively same age must is pregnant take the outpatient servicephysical examination health the woman as 42 examples makes the control group. Line of doublelower limb deep vein colored Doppler supersonic inspects whether has the thrombus to form andthe symptomless thrombus formation, And surveys two-sided CFV, SFV, POPV, the PTV insidediameter and two-sided CFV, the POPV vein blood stream frequency spectrum peak value,simultaneously the convention draws blood examines PLT, HGB, HCT, D-D, TT, APTT, PT, theFbgC value. Statistics software carries on statistics processing using SPSS the 13.0 to the data.(±s)indicated to all determination data by the mean value±standard deviation that, each group ofdata carry on the variance homogeneity examination, each group of mean value comparison utilization variance analysis; The variance analysis has the significance difference line furthermultiple comparisons: The variance homogenous 22 comparisons applies the SNK examination,the variance uneven 22 comparisons applies Dunnett' s the T3 examination.Results1. The full-term pregnant women with the high-risk thrombus factor has more diffrencecompare with healthy pregnant women: The double lower limb inside diameter obviouslyincreases the width, the blood stream frequency spectrum peak value obviously reduces, PLT,HGB, HCT, D-D, TT, APTT, PT, FgbC obviously change, prompt the pregnant woman to behealthy must are pregnant the woman to be in PTS.2,The high-risk factor full-term pregnant woman group double lower limb deep vein insidediameter and the blood stream speed in the supersonic under change (A group): Experimentalgroup A1 and experimental group A2 compares: The left/right flank CFV inside diameter(1.37±0.16 vs 1.13±0.14/1.35±0.24 vs 1.12±0.12), left side the SFV inside diameter (0.73±0.09vs 0.65±0.08) obviously increases the width, the left/right flank POPV blood stream frequencyspectrum peak value (5.02±1.25 vs 7.08±2.10/4.98±1.26 vs 6.96±2.26) obviously reduces,HCT(33.99±3.33 vs 31.66±4.02), D-D(296.02±140.70 vs 249.05±90.16) remarkable markup, thedifference has the remarkable significance (P=0.000/0.000, 0.000,0.000,0.000,0.002); Left sidethe POPV inside diameter (0.69±0.08 vs 0.66±0.06) increases the width, the difference hasstatistics significance (P=0.034); Right flank SFV inside diameter (0.73±0.08 vs 0.71±0.10),right flank POPV inside diameter (0.67±0.09 vs 0.65±0.08), left/right flank PTV inside diameter(0.32±0.05 vs 0.33±0.08/0.32±0.06 vs 0.31±0.05), The left/right CFV blood stream frequencyspectrum peak value (7.87±3.16 vs 8.984±4.12/7.97±3.44 vs 8.77±3.21), PLT(165.51±29.22 vs167.85±28.35), HGB(106.01±12.62 vs 108.89±11.06), TT(13.28±1.63 vs 13.27±1.21),APTT(30.75±2.17 vs 30.184±2.62), PT(13.40±2.48 vs 13.80±2.86), FbgC(3.48±0.91 vs3.46±0.78) changes not obviously, difference non-statistics significance (P=0.232, 0.076,0.903/0.836, 0.179/0.116, 0.617, 0.300, 0.403, 0.834, 0.224, 0.724).Experimental group A1 andthe control group compare: Left/right flank CFV(1.37±0.16 vs 0.72±0.05/1.35±0.24 vs 0.71±0.03), left/right flank SFV(0.73±0.09 vs 0.52±0.04/0.73±0.08 vs 0.52±0.03),POPV(0.69±0.08 vs 0.50±0.04/0.67±0.09 vs 0.49±0.03), PTV(0.32±0.05 vs0.25±0.03/0.32±0.06 vs 0.26±0.03) inside diameter obviously increases the width, Theleft/right flank CFV blood stream frequency spectrum peak value (7.87±3.16 vs17.21±3.57/7.97±3.44 vs 17.98±2.52), the left/right flank POPV blood stream frequencyspectrum peak value (5.02±1.25 vs 12.64±3.18/4.98±1.26 vs 12.30±4.05) obviously reduces,PLT(165.51±29.22 vs 193.62±35.00), HGB(106.01±12.62 vs 123.50±5.59), HCT(33.99±3.33 vs38.86±2.84), D-D(296.02±140.70 vs 168.62±36.68), TT(13.28±1.63 vs 12.60±1.13),APTT(30.75±2.17 vs 26.62±2.11), PT(13.40±2.48 vs 11.57±0.79), FbgC(3.48±0.91 vs 2.56±0.58)obviously changes, the difference has the remarkable significance (P＜0.01). Experimentalgroup A2 and the control group compare: The left/right flank CFV inside diameter (1.13±0.146vs 0.72±0.05/1.12±0.12 vs 0.71±0.03), the left/right flank SFV inside diameter (0.65±0.08 vs0.52±0.04/0.71±0.10 vs 0.52±0.03), the left/right flank POPV inside diameter (0.66±0.06 vs0.50±0.04/0.65±0.08 vs 0.49±0.03), the left/right flank PTV inside diameter (0.33±0.08 vs0.25±0.03/0.31±0.05 vs 0.26±0.03) obviously increases the width, The left/right flank CFVblood stream frequency spectrum peak value (8.98±4.12 vs 17.21±3.57/8.77±3.21 vs17.98±2.52), the left/right flank POPV blood stream frequency spectrum peak value (7.08±2.10vs 12.64±3.18/6.96±2.26 vs 12.30±4.05) obviously reduces, PLT(167.85±28.35 vs193.62±35.00), HGB(108.89±11.06 vs 123.50±5.59), HCT(31.66±4.02 vs 38.86±2.84),D-D(249.05±90.16 vs 168.62±36.68), TT(13.27±1.21 vs 12.60±1.13), APTT(30.18±2.62 vs26.62±2.11), PT(13.80±2.86 vs 11.57±0.79), FgbC(3.46±0.78 vs 2.56±0.58) obviously changes,the difference has the remarkable significance (P＜0.01).3. The thrombus forms the high-risk factor pregnant woman post-natal 2-5 day groupdouble lower limb deep vein inside diameter and the blood stream speed in the supersonic underchange (B group): Experimental group B1 and experimental group B2 compares: Left/right flankCFV inside diameter (0.97±0.17 vs 0.91±0.13/0.96±0.15 vs 0.89±0.11), The left/right flank SFVinside diameter (0.62±0.05 vs 0.55±0.06/0.62±0.06 vs 0.56±0.07), the left/right flank POPV inside diameter (0.58±0.06 vs 0.55±0.05/0.57±0.06 vs 0.54±0.05) obviously increases the width,D-D(320.88±276.32 vs 237.14±109.62) remarkable markup, the difference has the remarkablesignificance (P＜0.01); The left/right flank POPV blood stream frequency spectrum peak value(8.45±2.96 vs 9.62±3.74/8.87±3.30 vs 9.88±2.28) reduces, the difference has statisticssignificance (P=0.011/0.042); Left/right flank PTV inside diameter (0.29±0.04 vs0.28±0.04/0.30±0.04 vs 0.29±0.02), left/right CFV blood stream frequency spectrum peak value(12.76±4.38 vs 12.94±3.93/12.81±5.77 vs 13.75±6.37), PLT(177.40±35.43 vs 176.95±36.19),HGB(103.94±12.66 vs 105.91±11.79), HCT(33.05±3.67 vs 33.57±3.55), TT(15.27±4-4.12 vs16.12±4.15), FgbC(3.39±0.92 vs 3.41±0.96), APTT(32.76±3.38 vs 32.24±3.45), PT(14.32±1.97vs 14.23±1.84) changes not obviously, difference non-statistics significance (P=0.203/0.160,0.982/0.592,0.925, 0.527, 0.278, 0.336, 0.999, 0.584, 0.851). Experimental group B1 and thecontrol group compare: The left/right flank CFV inside diameter (0.974±0.17 vs0.72±0.05/0.96±0.15 vs 0.71±0.03), the left/right flank SFV inside diameter (0.62±0.05 vs0.52±0.04/0.62±0.06 vs 0.52±0.03), the left/right flank POPV inside diameter (0.58±0.06 vs0.50±0.04), the left/right flank PTV inside diameter (0.29±0.04 vs 0.25±0.03/0.30±0.04 vs0.26±0.03) obviously increases the width, The left/right flank CFV blood stream frequencyspectrum peak value (12.76±4.38 vs 17.21±3.57/12.81±5.77 vs 17.98±2.52), the left/right flankPOPV blood stream frequency spectrum peak value (8.45±2.96 vs 12.64±3.18/8.87±3.30 vs12.30±4.05) obviously reduces, PLT(177.40±35.43 vs 193.62±35.00), HGB(103.94±12.66 vs123.50±5.59), HCT(33.05±3.67 vs 38.86±2.84), D-D(320.88±276.32 vs 168.62±36.68),TT(15.27±4.12 vs 12.60±1.13), FgbC(3.39±0.92 vs 2.56±0.58), APTT(32.76±3.38 vs26.62±2.11), PT(14.32±1.97 vs 11.57±0.79) obviously changes, the difference has theremarkable significance (P＜0.01). Experimental group B2 and the control group compare: Theleft/right flank CFV inside diameter (0.91±0.13 vs 0.72±0.05/0.89±0.11 vs 0.71±0.03), theleft/right flank SFV inside diameter (0.55±0.06 vs 0.52±0.04/0.56±0.07 vs 0.52±0.03), theleft/right flank POPV inside diameter (0.55±0.05 vs 0.50±0.04/0.54±0.05 vs 0.49±0.03), theleft/right flank PTV inside diameter (0.28±0.04 vs 0.25±0.03/0.29±0.02 vs 0.26±0.03) obviously increases the width, left/right flank CFV blood stream frequency spectrum peak value(12.94±3.93 vs 17.21±3.57/13.75±6.37 vs 17.98±2.52), The left/right flank POPV blood streamfrequency spectrum peak value (9.62±3.74 vs 12.64±3.18/9.88±2.28 vs 12.30±4.05) obviouslyreduces, PLT(177.40±35.43 vs 193.62±35.00), HGB(103.94±12.66 vs 123.50±5.59),HCT(33.05±3.67 vs 38.86±2.84), D-D(320.88±276.32 vs 168.62±36.68), TT(15.27±4.12 vs12.60±1.13), APTT(32.76±3.38 vs 26.62±2.11), PT(14.32±1.97 vs 11.57±0.79), FgbC(3.39±0.92vs 2.56±0.58) obviously changes, the difference has the remarkable significance (P＜0.01).4. The thrombus forms the high-risk factor pregnant woman post-natal 42-45 day groupdouble lower limb deep vein inside diameter and the blood stream speed in the supersonic underchange: Experimental group C1 and experimental group C2 compares: Left/right flank CFVinside diameter (0.71±0.04 vs 0.70±0.04/0.70±0.04 vs 0.69±0.03), left/right flank SFV insidediameter (0.51±0.03 vs 0.52±0.04/0.51±0.04/0.52±0.04), left/right flank POPV inside diameter(0.49±0.03 vs 0.51±0.04/0.48±0.04 vs 0.49±0.04), left/right flank PTV inside diameter(0.26±0.03 vs 0.25±0.02/0.27±0.03 vs 0.26±0.03), left/right flank CFV blood stream frequencyspectrum peak value (17.59±4.53 vs 18.37±3.80/17.53±3.78 vs 18.46±3.30), The left/right flankPOPV blood stream frequency spectrum peak value (11.79±3.81 vs 12.19±3.61/11.95±4.15 vs12.06±4.18) and PLT(197.69±31.90 vs 200.29±29.41), HGB(121.98±7.53 vs 124.00±6.69),HCT(38.07±2.80 vs 37.76±2.63), D-D(165.82±34.96 vs 168.24±31.68), TT(13.01±1.81 vs12.97±1.39), APTT(26.99±2.10 vs 26.41±1.90), PT(11.55±0.81 vs 11.67±0.92), FbgC(2.66±0.60vs 2.71±0.68) each group of level comparison, the difference does not have statistics significance(P＞0.05). Experimental group C1 and the control group compare: Left/right flank CFV insidediameter (0.71±0.04 vs 0.72±0.05/0.70±0.04 vs 0.71±0.03), left/right flank SFV inside diameter(0.51±0.03 vs 0.50±0.04/0.51±0.04 vs 0.52±0.03), left/right flank POPV inside diameter(0.49±0.03 vs 0.50±0.04/0.48±0.04 vs 0.49±0.03), left/right flank PTV inside diameter(0.26±0.03 vs 0.25±0.03/0.27±0.03 vs 0.26±0.03), left/right flank CFV blood stream frequencyspectrum peak value (17.59±4.53 vs 17.21±3.57/17.53±3.78 vs 17.98±2.52), The left/right flankPOPV blood stream frequency spectrum peak value (11.79±3.81 vs 12.64±3.18/11.95±4.15 vs 12.30±4.05) and PLT(197.69±31.90 vs 193.62±35.00), HGB(121.98±7.53 vs 123.5±5.59),HCT(38.07±2.80 vs 38.86±2.84), D-D(165.82±34.96 vs 168.62±36.68), TT(13.01±1.81 vs12.60±1.13), APTT(26.99±2.10 vs 26.62±2.11), PT(11.55±0.81 vs 11.57±0.79), FbgC(2.66±0.60vs 2.56±0.58) each group of level comparison, the difference does not have statistics significance(P＞0.05). Experimental group C2 and the control group compare: Left/right flank CFV insidediameter (0.70±0.04 vs 0.72±0.05/0.69±0.03 vs 0.71±0.03), left/right flank SFV inside diameter(0.52±0.04 vs 0.50±0.04/0.52±0.04 vs 0.52±0.03), left/right flank POPV inside diameter(0.51±0.04 vs 0.50±0.04/0.49±0.04 vs 0.49±0.03), left/right flank PTV inside diameter(0.25±0.02 vs 0.25±0.03), left/right flank CFV blood stream frequency spectrum peak value(18.37±3.80 vs 17.21±3.57), The left/right flank POPV blood stream frequency spectrum peakvalue (18.46±3.30 vs 17.98±2.52) and PLT(200.29±29.41 vs 193.62±35.00), HGB(124.00±6.69vs 123.5±5.59), HCT(37.76±2.63 vs 38.86±2.84), D-D(168.24±31.68 vs 168.62±36.68),TT(12.97±1.39 vs 12.60±1.13), APTT(26.41±1.90 vs 26.62±2.11), PT(11.67±0.92 vs11.57±0.79), FbgC(2.71±0.68 vs 2.56±0.58) each group of level comparison, the difference doesnot have statistics significance (P＞0.05).Conclusion1. The full-term pregnant women with the high-risk thrombus factor has more diffrencecompare with healthy pregnant women: The double lower limb inside diameter obviouslyincreases the width, the blood stream frequency spectrum peak value obviously reduces, PLT,HGB, HCT, D-D, YY, APTT, PT, FgbC obviously change, prompt the pregnant woman to behealthy must are pregnant the woman to be in PTS.2. Thrombus to form the high-risk factor to be pregnant the full-term pregnant womandouble lower limb multi-strip vein inside diameter and the vein blood stream frequency spectrumpeak value and the healthy pregnant woman compares has had the remarkable change, themajority of lower limb vein inside diameter obviously increased the width, the partial bloodstream frequency spectrum peak value obviously reduced, left side SFV, the POPV insidediameter increased the width obviously, right flank changed not not obviously, HCT obviously reduced, the D-D remarkable ascension, prompted is pregnant full-term has the high-risk factorparturient woman to compare the health full-term pregnant woman to be in obvious PTS, andprompted the left lower limb deep vein possibly to be at in front of the thrombus compared to theright lower limb change the condition; Has the thrombus to form the high-risk factor to bepregnant the full-term pregnant woman, the healthy pregnant woman must is pregnant with thehealth the pregnant woman to compare separately: The double lower limb inside diameterobviously increases the width, the blood stream frequency spectrum peak value obviouslyreduces, PLT, HGB, HCT, D-D, TT, APTT, PT, FgbC obviously change, prompt the pregnantwoman to be healthy must are pregnant the woman to be in obvious PTS.3.The post-natal 2-5 day-long parturient woman and the health who the thrombus forms thehigh-risk factor the parturient woman compares same time, the D-D remarkable markup, itslower limb vein inside diameter and the vein blood stream frequency spectrum peak valuechange with is pregnant the full-term pregnant woman's findings to be approximate, prompts thechild's bed early time to have the high-risk factor child's bed early time parturient woman healthysame time parturient woman to be in obvious PTS; Has the post-natal 2-5 day-long parturientwoman, the health who the thrombus forms the high-risk factor the parturient woman separatelywith the health must is pregnant the woman to compare same time, with is pregnant the full-termfindings basic similar, prompts the child's bed early time pregnant woman to be healthy must ispregnant the woman to be in obvious PTS.4. The thrombus to form the high-risk factor the post-natal 42-45 day-long parturientwoman double lower limb multi-strip vein inside diameter, the vein blood stream frequencyspectrum peak value and the blood target and the healthy parturient woman and the health mustis pregnant the woman 22 to compare not obviously changes.5. Double lower limb deep vein colored Doppler supersonic the condition has certainclinical value in front of the forecast perinatal stage high-risk group thrombus, has certain fittingwith the laboratory inspection obtained result, between both may supplement mutually.6. Applies the high resolution colored Doppler supersonic inspection pregnant woman double lower limb 664 people, must is pregnant the healthy woman 42 people, had notdiscovered the obvious thrombus forms and the symptomless thrombus formation.
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