Analysis On Prognostic Factors Of Nasopharyngeal Carcinma Of Uygur And Han Of 143 Patients

Objective: The prognostic factors of 143 patients of Uygur and Han in XinJiang Tumour Hospital with nasopharyngeal carcinoma(NPC)treated by conventional radiotherapy were analysed retrospectively, to evaluate the result of and prognostic factors. Methods: From September 1999 to December 2007, to select preliminarily diagnosed patients of 87 Han and 56 Uygur with nasopharyngeal carcinoma. The variables age, sex, T stage, N stage, clinical stage pathology category, invasion of skull base, carinial nerve involvement cervical lymph nodes metastasis, residual nasopharyngeal carcinoma and the dose of radiation were evaluated the significance of prognostic variables in the survival by univariate analysis and Cox stepxisse regression model. Results: The patients of Han with nasopharyngeal carcinoma, The 1, 3, 5year overall survival rates were 96.25%, 86.21%, 62.07%. Univariate analysis suggested that age, T stage, N stage, clinical stage, invasion of skull base, carinial nerve involvement cervical lymph nodes metastasis were significant factors for prognosis(P<0.05). Multiplt factors analysis suggested that clinical stage, invasion of skull base were significant factors for prognosis(P<0.05). The patients of Uygur with nasopharyngeal carcinoma, The 1, 3, 5 year overall survival rates were 94.64%, 76.79%, 51.79%. Univariate analysis suggested that age, N stage, pathology category, invasion of skull base, carinial nerve involvement, residual nasopharyngeal carcinoma were significant factors for prognosis(P<0.05). Cox analysis suggested that age, N stage, invasion of skull base were significant factors for prognosis(P<0.05). Conclusions: age, carinial nerve involvement, clinical stage, invasion of skull base were significant factors for prognosis.Compared Uygur and Han, The prognosis of patients of Uygur with nasopharyngeal carcinoma were worse than Han.