Clinical Manifestation Of GD And Clinical Significance Of Determination Of Sera FT3,FT4,TSH,TPOAb In Exophthalmos Patients With GD

Objective To investigate the value of sera FT3,FT4,TSH,TPOAb in exophthalmos patients with Graves'disease; To summarize and analyze the topography of the clinical manifestation of GD, such as exophthalmos. lid retraction .lid fullness. hypophasis hyperremia and edema of conjunctiva .disorder of ocular movement and so on. Methords collect and analyze the clinical manifestation of 207 patients with Graves'disease who want to accept radioiodine therapy;sera FT3,FT4,TSH,TPOAb levels were measured and compared in 125 exophthalmos patients with GD, 82GD patients. Results exophthalmos were present in125 (60.38%) cases. lid retraction 169 (81.64%). hypophasis 176(85.02%). lid fullness 88 (42.51%). hyperremia and edema of junctiva 92(44.44%). disorder of ocular movement 16(7.73%); corneal edema or ulcer3(0.145%).sera FT3,FT4,TSH,TPOAb levels in two patients groups had no significant difference (P>0.05). Conclusions patients in two groups were all in high secretor state; different clinical manifestations were over present in over 85% patients, diagnose and treatment of Thyroid-associated ophthalmopathy(TAO) can't be ignored.