Comparison Of The Use Of Intermittent Pneumatic Compression System With The Use Of Low-molecular-weight Heparin For The Prevention Of Deep-vein Thrombosis After Total Hip Replacement

ObjectiveTo compare the safety and effectiveness of the intermittent pneumatic compression system with that of low-molecular-weight heparin for reducing the prevalence of deep-vein thrombosis after total hip replacementMethodsWe performed a randomized trial in 61 patients to evaluate the effectiveness and safety of low-molecular-weight heparin as compared with the intermittent pneumatic compression system to prevent deep-venous thrombosis after total hip replacement. Patients in low-molecular-weight heparin group were given 0.2ml subcutaneously daily,patients in intermittent pneumatic compression groups were treated by intermittent pneumatic compression system from 5h after surgery till 14 days after surgery.Quality detect plasma D- dimer and P- selectin in two groups and patients were examined by Color Doppler Flow Imaging on one day before surgery and the third day after surgery and the seventh days after surgery respectively.ResultsThere were 3 patients and 2 patients with deep-vein thrombosis in the intermittent pneumatic compression system group and low-molecular-weight heparin group respectively.No patient developed clinical features of a pulmonary embolism.There were no significant between these two groups(P＞0.05)ConclusionsThis study confirms the safety and efficacy of foot pump compared with low-molecular-weight hepadn and supports the use of mechanical compression for prophylaxis against deep venous thrombosis in patients who have had a total knee arthroplasty.