| Objective To study the changes of three coagulation parameters and blood platelets count in patients with esophageal carcinoma,gastric carcinoma and rectal cancer and its clinical significance. Method PLT,PT,APTT,TT,FBG levels of 99 normal terms and 185 esophageal carcinoma patients,gastric carcinoma patients and rectal cancer patients which included 56 esophageal carcinoma patients,60 gastric carcinoma patients,69 rectal cancer patients were examined by CA7000 and XE2100. Results 1.As compared with normal terms,PT,APTT,FBG and PLT were significantly different in esophageal carcinoma patients;gastric carcinoma patients and rectal cancer patients(p<0.05). 2.In different period of esophageal carcinoma patients;gastric carcinoma patients and rectal cancer patients, PT,APTT,FBG and PLT of termâ… toâ…¡were higher apparently than normal terms (p<0.05),3. In different period of esophageal carcinoma patients,gastric carcinoma patients and rectal cancer patients.As compared withâ… toâ…¡terms,FBG of termâ…¢to IV were higher apparently (p<0.05). while PT,APTT and PLT have a high tendency,but there was no difference.4.There were significantly different between normal term,â…¢to IV term andâ… toâ…¡term. Conclusion The higher of FBG and PLT indicate that it exists blood hypercoagulabale state in esophageal carcinoma patients,gastric carcinoma patients and rectal cancer patients.The prolongation of PT,APTT,TT in blood plasma indacate that esophageal carcinoma patients,gastric carcinoma patients and rectal cancer patients have alimentary tract hemorrhage tendency.The detection of PT,APTT,TT,FBG and PLT may play a specific role in the laboratory examination of esophageal carcinoma patients;gastric carcinoma patients and rectal cancer patients.according to these marks we can determing whether or not giving patients anticoagulation and haemostasis treatment and to prognosticate neoplastic occurrence,infiltration and transfusion.
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