| Objective: By analyzing the pediatric surgery in our hospital fromJanuary 1987 to January 2007 the treated children withcongenital biliary dilatation, the procedure used forremoval hepatic duct cyst Roux-Y anastomosis and liverbiopsy 58 cases, expansion of congenital biliary dilatationcaused biliary cirrhosis of the clinical factors. And bymeasuring children with congenital biliary dilatation of theindicators of liver function and the level of liver CDFI,compared before and after surgery in children with thechanges in liver function and cirrhosis of the vestingconditions. Application of the results of the study guideclinical treatment and evaluation of the prognosis.Method: According to the postoperative pathology report ,We dividedthe study subjects into three groups: Cirrhosis group, Earlycirrhosis group and normal liver cells, the children wereeach the following address: preoperative and intraoperativecareful determination of the location of cysts, morphology,size, preoperative liver function within a week of relevantindicators, including T-BIL,D-BIL,A/G,AST,ALT,ALP, GGT, and cysts and liver were examined by Color Doppler; Observed in the liver of general pathology, small liver specimens from the right lobe of the liver edge were sent pathological examination; Within six months after the patient referral request again the determination of liver function and liver CDFI review, the results of each group as preoperative and postoperative group, using statistical methods for analysis and treatment the results.Result: Children with cirrhosis group cyst size, on average higherthan other two groups, the pathological damage to the liverwas more serious; On the age distribution Cirrhosis groupwas significantly less than the other two groups, thedifference was significant; Comparison of liver functionrelated indicators of the postoperative group and the groupof preoperative, the difference was significant;Thecirrhosis group was Detected by Color DopplerUltrasonography after surgery, the majority of childrenwith liver pathology damage was obviously improvedConclusion:â‘ Biliary obstruction is the result of congenital biliarydilatation of the main reasons for damage to the liverpathology, congenital biliary dilatation of children withtype I cyst is, the greater the impact of bile flow dynamics, the greater the impact of the liver.â‘¡Children with congenital biliary dilatation of the smallerage of onset, symptoms sooner, the greater theopportunity to cirrhosis.â‘¢We should maintain a positive attitude to the childrenwith congenital biliary dilatation merger biliarycirrhosis, which may have reversed after lifting biliaryobstruction. |