| As a primary chronic disease, arthritis has seriously influenced people especially the elder's life. It has been a major reason causing pain and disability. Starting from the heat and mass transfer principles, this paper is dedicated to present an investigation on the temperature prediction in the process of arthritis, cold treatment and hyperthermia, the production and disposal of effusion, the relief of pain, and the improvement of lubrication. Some main achievements as obtained in this thesis are listed as follows:1. The three-dimensional grid model for calculating thermal issues of human knee with real configuration was established. Through using the classical Pennes bioheat transfer equation, the temperature fields of normal knees and pathological ones were numerically simulated, which would provide theoretical foundation for thermal diagnoses. The effect of non-intervention hyperthermia in vitro and intervention hyperthermia based on vessel heating were evaluated.2. Based on the mass transfer theory, the micro circulation model of capillary vessel was established. And it was utilized to interpret why the effusion is produced. The effects of cold treatment and hyperthermia in the disposal of effusion were analyzed.3. Based on the fundamental theory of neurology, the phenomenon that cold treatment and hyperthermia can relieve the pain was explained by way of calculating the H-H Model. The periodicity of neural excitation was analyzed via introducing chaos map. The influence of the concentration of ions in tissue fluid on neural excitation was analyzed.4. Artificial synovia was prepared and its rheology was measured. The effects of molecular weight and concentration of hyaluronate, and temperature on the rheology of artificial synovia were studied, and the conclusion can also be used in natural synovia.
|
PDF Full Text Request