SuZhiXiaoZhongGao To The Acute Soft Tissue Damage Animal Model Removing Extravasted Blood Pain-Relieving Function Exper Imental Study

[Objective]Discusses the possible removing extravasted blood pain relieving function mechanism of SuZhiXiaoZhongGao,provides the scientific basis for the clinical new medicine application and the promotion.[Method]Establishes the acute soft tissue to damage the big mouse model, observes SuZhiXiaoZhongGao and the comparison medicine safflower oil damages the big mouse outward appearance and the histology,the blood rheology influence to the acute soft tissue,discusses it in the promotion damage soft tissue repair as well as the blood circulation removing extravasted blood aspect function;Turns the body law through the mouse, observes SuZhiXiaoZhongGao and the comparison medicine safflower oil sends the mouse ache inhibitory action to the glacial acetic acid,discusses it in the analgesia aspect function.[Result]SuZhiXiaoZhongGao to damage the big mouse histology and the blood rheology influence to the acute soft tissue:The medicine treatment group damages the partial hemorrhage,the ecchymosis and dropsy area as well as muscle fiber necrosis,the phlogocyte infiltration degree obviously is short in the control group,the model group(P＜0.05 or P＜0.01),approaches in the blank group;Medicine treatment group blood rheology each target is lower than the control group,the model group obviously(P＜0.05 or P＜0.01), approaches in the blank control group,Because SuZhiXiaoZhongGao Foreign to send the mouse ache inhibitory action;SuZhiXiaoZhongGao to have the obvious analgesia function to the glacial acetic acid result mouse ache (Labor pain rate＞50%);The control group,the treatment group and the blank group and turns in the body number of times in the incubation period to have the extremely remarkable difference(P＜0.01).also control group and treatment group analgesia function similar(P＞0.05).[Conclusion]SuZhiXiaoZhongGao to be able to promote the acute soft tissue to damage the big mouse partial swelling,the ecchymosis dissipation,speeds up the damage organization to repair,reduces the treatment time;Can improve the acute soft tissue to damage the big mouse blood rheology target obviously,achieves blood circulation removing extravasted blood the effect; Can improve the recurrent state,enhances the pain to clarify the value, thus plays the good analgesia role.