Retrospective Study Of MRI-DWI On Different TCM Diagnosis In Acute Ischemia Stoke

ObjectiveTo investigate the relationship between MRI-DWI appearance and different TCM diagnosis, 206 cases of acute ischemia stroke were retrospectively analyzed. MRI-DWI is aimed to be used as an objective index for TCM classifications in this study.Methods206 patients (male 123, female 83) were selected and grouped according to 'Guide principles on clinical research of New TCM drugs ' .Their MRI imaging were interpreted on the location, size, ADC value et al of lesion. SPSS 13.0 was employed for Statistical analysis.Results1. ADC value of infarcted area shows a sharp declination in acute stage, therefore acute infarction appears as hyper-intensity on MRI-DWI. The differences between ADC values of acute infarcted area and normal tissue are statistically significant(P=0.0000 < 0.05).2. The ADC values between different TCM patterns showed no statistical significance (P>0.05).3. In TCM diagnosis of the study, Zhongjingluo was more common than zhongzangfu, the ratio is 19:1. The predilection of specific subtype TCM patterns were found in this study.4. In patients of large area cerebral infarction, TCM diagnosis showed the same predilection: zhongjingluo-84.8%, zhongzangfu-15.2%.Conclusion1. The MRI-DWI is effective in detecting acute ischemia infarction.2. The ADC values between different TCM patterns are not specific, therefore, ADC value as an objective index in TCM diagnosis classification is required to be further studied. 3. Zhongjingluo is the more common pattern than zhongzangfu in acute ischemia apoplexy and a special subtype of TCM patterns predominates in Zhongjingluo. The injury to body of acute stroke was related to location and size of infarction.4. In large area cerebral infarction, Zhongjingluo is more frequent than zhongzangfu in TCM diagnosis.