The Clinical Studies Of Yiqixinnaoning To Prevent And Treat Cerebral Infarction Combined Angina Of Coronary Atherosclerosis Heart Disease

Objective:To investigate the curative efficiencies of Yiqixinnaoning on patients with cerebral infarction combined cerebral infarction combined angina of coronary atherosclerosis heart disease(CAHD),and its biological mechanism of curative effect. We may provide new theoretical guidance on treatment ischemic angiocardiopathy and cerebrovascular disease by using Traditional Chinese Medicine.Methods:Clinical studying methods:20 cases with cerebral infarction combined CAHD were taken as objects,and treatmeant with chinses medicine Yiqixinnaoning.The whole course of was 4 weeks.By means of comparative the curative effect for patients per as before and atfter therapy and between treatment group and control group which treated with Tongxinluojiaonang,the observations on effects were made.The indexes of curative effects included such as: clinical symptoms integrals;nervus dysfunctions system(NIHSS),gnosia(MMSE), viability(Barthel),ECG,cardiac function,blood-lipid,blood rheologp,the functions of endothelial cell,and etc.The safety evalutions were surveillanced at the same time,which included:Blood routine examination,routine uronoscopy,fecal routine examination,liver and renal functions and so on.Results:The scores declined after 4 weeks treatment.The indexes of NIHSS,MMSE,viability,frequencies and continude-time of angina pectoris, ECG,cardian function were all improvement too.The outcomes of statistic showed that, the indexes above of Yiqixinnaoning were better than that of the group of Tongxinluojiaonang(P＜0.05).Conclusions:Yiqixinnaoning possessed the comfired protective functions to angiocardiopathy and cerebrovascular.The studies showed that,the common pathogenesis of cerebral infarction and CAHD were deficiency of qi and blood stasis,pathogens injuried the collateral branch of the large channel.The important principle in treatment on ischemic angiocar diopathy and cerebrovascular disease were supplementing qi and promoting blood,removing toxic substances and removing obstruction in the channel,and treatment heart and brain with the same methods. Yiqixinnaoning possessed notebale curative effect;it was the effctive complex prescription for the treatment of ischemic angiocardiopathy and cerebrovascular disease.