Comparative Analysis Between Partial Cystectomy And Radical Cystectomy Of T₂ Urothelial Bladder Carcinoma

Objective: To study T₂ urothelial bladder carcinoma patients underwent radical cystectomy and partial cystectomy, then find the influence of two operation manners on survival rate.Methods: The clinical data, histopathological reports and follow-up results of T₂ urothelial bladder carcinoma patients underwent radical cystectomy and partial cystectomy in our department from 1990 to 2005 were studied retrospectively.Results:From January 1990 to December 2005,238 of 1293 patients(18.4%),including 196 males (82.4%) and 42 females(17.6%),were found to have pathological muscle invasive (T2) urothelial bladder carcinoma following radical cystectomy and partial cystectomy. They were all new cases. The average age was 64-year-old. Of this group 168 patients(70.6%)was underwent partial cystectomy and 70 patients(29.4%)underwent radical cystectomy,No significant difference was observed in 3-year survival rate between patients underwent radial cystectomy and patients underwent partial cystectbmy(80.2% vs 77.6% P>0.05),but difference was observed in 5-year survival rate and 10-year survival rate between patients underwent radial cystectomy and patients underwent partial cystectomy(70.2% vs 51.8% P<0.01; 49.5% vs 32.4% P<0.05).Conclusion: the first operation manner have influence on the survival rate of T₂ urothelial bladder carcinoma patients, patients underwent radical cystectomy have better survival rate than patients underwent partial cystectomy.