| Objective: To analyse the factors that influence blood albumin level in liver cancer patients who received hepatectomy and to discusse effective measures for the management of postoperative hypoproteinemia. Method: Data from 250 cases with liver cancer received hepatectomy from September 2005 to November 2007 were analysed. All cases were classified various groups according to the factors of preoperative status, surgery operation, and postoperative management. Preoperative and postoperative day1,day3,day 7serum albumin levels were analyse in relation to the classify factors. The relationship between different serum albumin level and hepatic inadequacy and death was also analysed. Result: There was no significant difference in serum albumin level among different groups of age,sex,HBsAg/HCVAb, hypersplenism at preoperative and postoperative day1, day3 , days7 serum albumin level. There were significant difference of preoperative and postoperative day7 serum albumin level for hepatic cirrhosis degree and Child grade. There were also significant difference serum albumin level in postoperativeday1,day3 for factors include tumor diameter,resection volume,operation time, spleen resection, hepatic vascular exclusion, blood loss. There were no significant difference for amino acids dose, quantity of hepatinica at preoperative and postoperative day1, day3, day7 serum albumin level. There was also significant difference of serum albumin level for infection and enteral nutrition at postoperative day7. Dose of human albumin have significant difference at postoperative day7 serum albumin level. Conclusion: Surgery wound is the major factor that influence postoperative serum albumin level at early stage. liver background and function is the major factor that influence postoperative serum albumin level at later stage. Active prevention and cure infection and administration enteral nutrition as early as possible is the major measures to improve postoperative serum albumin level. |
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