The Study Of Functional And Structural Changes Of Left Ventricle In Patients With Pregnancy-Induced Hypertension Using Strain Rate Imaging

Objection To assess the feasibility of using strain rate imaging to evaluate functional and structural changes of left ventricle in patients with pregnancy-induced hypertension (s-pe). Methods 20 patients with Preeclampsia and 21 normal pregnant controls are included. Left ventricular ejection fraction (EF), left ventricular mass index (LVMI), mitral early diastolic peak flow velocity (E), late diastolic peak flow velocity (A), E/A ratio, systolic pulmonary venous atrial Reverse flow peak filling (AR), the brachial artery systolic and diastolic blood pressure, the peak systolic myocardial strain rate (SRS), early diastolic peak strain rate (SRe), the late diastolic peak strain rate (SRa) are recorded. Results Anterior wall of the basement (BaS) and middle (Mid) and SRe SRS in left ventricle are significantly lower than the control group (P <0.05, respectively). E, E/A and left ventricular EF values in patients with s-pe are significantly lower than the control group (P <0.05, respectively). While mitral late diastolic filling peak (A), atrial systolic pulmonary venous filling peak reverse flow (AR), relative wall thickness Room, the brachial artery systolic and diastolic blood pressure are significantly higher than the controls(P <0.05, respectively). Conclusion There are left ventricle structural abnormalities in patients with s-pe, and with significant reduction in left ventricular mechanical function. Strain rate imaging appears to be a clinically applicable and reliable imaging technique that allows quantitative assessment cardiac function of s-pe.