The Effect Of Pneumoperitoneum On Respiratory And Circulation System Of The Obesity During Laparoscopic Cholecystectomy

Objective To research the effect of pneumoperitoneum on respiratory and circulation system of the obesity during laparoscopic cholecystectomy.Methods 22 patients who received elective laparoscopic cholecystectomy were divided into 2 groups according to the BMI:control group (group A):BMI =22±3; obesity group (group B): BMI BMI=35±4 .All patients were ASA physical status I or II, non-smokers, and free of cardiac,pulmonary, renal or neuromuscular disease. The HR, SBP, DBP, PETC02, PAW, SPO2 of group A and group B were analyzed at the different time: before insufflation, 5 min after insufflation, 15 min after operation,30 min after operation.Data are means±SD. Effects of weight and abdominal insufflation were analyzed by repeated measures analysis of variance. And then we can described polyline maps.Results Pneumoperitoneum caused a significant lncrease in HR,SBP,Peak and PetC02 (P<0.01) in morbidly obese patients or in the normal. Peak was higher in morbidly obese compared with normal·weight patients before or during pneumoperitoneum, either undergoing laparoscopic cholecystectomy or laparoscopie gynecologic operation (P<0.05).Conclusion Morbidly obesity and pneumoperitoneum have significant effects on respiratory mechanics. C02 pneumoperitoneum of laparoscopic cholecystectomy results in more significant effects in respiratory and circulation system on obesity patients.