Study On The Hepatoprotective Activity Of Non-Alkaloids Fraction From Radix Sophorea Tonkinensis

Radix Sophorae Tonkinensis has the function of clearing away heat and toxic materials and relieving pain. Ganyanling injection, which is made from traditional Chinese medicine Radix Sophorae Tonkinensis, has an obvious impact on decreasing the transaminase level.In this study, two fractionsâ… andâ…¡were separated from Radix Sophorae Tonkinensis by using ion exchange resin and dichloromethane extraction respectively. After investigated on HBV model, fractionâ… s howed a good ability of decreasing the transaminase level. Besides, the study on the immune function in mice suggested that fractionâ… can also enhance the immune function.What's more, the method for quality control of non-alkaloids fraction from Radix Sophorae tonkinensis had been established. Sugar, organic-acid, polyphenolic and saponin was identified by TLC. The contents of Sugar, polyphenolic and saponin were determined by spectrophotometry and the content of organic-acids was determined by acid-based titration. The stablility ability of fractionâ… had also been investigated.