Analysis Of 13 Cases Of Gastrointestinal Tract Carcinoid Tumors

Objective:To discuss the clinical manifestation,diagnostic methods,the therapy of gastrointestinal tract carcinoid tumors and analyse cases which were misdiagnosed,in order to improve the level of recognition and diagnosis.Methods:The data of 13 cases of gastrointestinal tract carcinoid tumors which were hospitalized during Jan,2004 and Oct,2008 were analysed retrospectively.Results:In our results,the average age of patients was 43.3.The internal from onset to be diagnosed was from 6 months to 10 years,with 18.7 months as average.The rectum is the most common site of carcinoids(53.8%),followed by the appendix (23.1%),then the esophagus,stomach and duodenal papilla is 7.7%respectively.The most common symptoms were abdominal pain(61.5%);changing of the habits of defecation(53.8%),nausea and vomiting(23.1%),bleeding of gastrointestinal tract (15.4%).CT was performed,in 4 cases,primory or metastasis was detected in 2 cases, and 2 were abnormal.Endoscopy was performed in 10 cases,positive findings were detected in 10 cases.6 cases got final diagnosis per endoscopy and biopsy,7 patients by operation and biopsy.Before final diagnosis,there was 1 case misdiagnosed for adeno-carcinoma,submucous tumor,small cell carcinoma and chronic inflammation of mucous membrane respectively,the carcinoids of appendix were all misdiagnosed for appendicitis.12 patients were taken a surgical resection,the rectum with hepatic metastases perfered four times of palliative systemic chemotherapeutic after endoscopic resection of primary carcinoids,another appendix carcinoid with lymph node involvement applied 5-fluorouracil after appendectomy.Conclusions:The clinical manifestations of gastrointestinal tract carcinoid tumors were non-specific.Abdominal pain and changing of the habits of defecation are the most commen symptoms.These neoplasms pose a diagnostic challenge.Biopsy is an imporment method to diagnose,but need to combined with CT and so on.Operation is the main approach to cure,and may need symphysial managements necessary,some of the carcinoids maybe cured by endoscope.