Effects Of Tongmai Oral Solution Hemodialysis On The Cardiac Structure Of Maintenance Hemodialysis Patients

BackgroungCardiovascular complications in chronic renal failure is the first cause of death.Maintenance of cardiovascular complications in dialysis patients the total mortality in dialysis patients per year of 10.4%-15.7%,about 40% of the world -45%of dialysis and transplant patients die of cardiovascular complications.Cardiovascular and chronic renal failure in maintenance hemodialysis patients to complications such as atherosclerosis,hypertension, heart failure,pericarditis,myocardial disease,such as.Recent study found that cardiovascular complications of chronic renal failure is the central link in inflammation and atherosclerosis,and malnutrition-inflammation-atherosclerosis (MIA) syndrome of chronic renal failure in the pathogenesis of vascular complications in the main role and much more is injected. Structural changes in cardiac function and left ventricular dysfunction is heart cavity expansion,left ventricular hypertrophy,diastolic and systolic dysfunction,myocarditis and pericarditis.With left ventricular hypertrophy and left ventricular diastolic dysfunction,the most prominent.In the clinical course,despite the use of a variety of drug treatment of cardiovascular complications,but their efficacy is still limited.We need to explore more effective ways to the maintenance of hemodialysis patients to prevent and treat cardiovascular complications,reduce maintenance hemodialysis patients with the mortality and improve the quality of dialysis, to extend the patient's life.Chinese medicine is widely used in clinical treatment of cardiovascular disease specialist,and achieved good effect,but in maintenance hemodialysis patients still need the use of further study.Tongmai Oral Solution consist multiple kind of Traditional Chinese Medicine,for example,Milkvetch Root and Sanchi etac.Previous clinical and experimental study have confirmed that the Tongmai Oral Solution can improve the patient's clinical symptom and renal function,decrease the proteinuria,adjust the immune function,ameliorate the blood rheology,lessen the renal pathological lesion,defer the glomerular sclerosis.We will use it in maintenance hemodialysis patients,one without the disadvantages of overloading the capacity of,and the other is taking to bring convenience for patients to observe the micro-inflammation, malnutrition and the impact of cardiac structure,involved in Chinese medicine for the treatment of hemodialysis to a certain degree of exploration.ObjectivesTo investigate the effect of Tongmai Oral Solution on cardiac function and structure in patients with end-stage renal disease during maintenance hemodialysis.MethodsChoice of chronic renal failure in maintenance hemodialysis patients 80 cases.Diabetic nephropathy,lupus nephritis and other kidney patients secondary to their incidence and stability should be controlled.All patients with the law 3 times a week hemodialysis,and careful control of blood pressure, fasting blood glucose(FBG),to correct anemia,such as routine treatment of antihypertensive drugs.According to SGA to assess nutritional status in patients with different,randomly divided into two groups of 40 people.Group for the blank control group,experimental group were given oral liquid for application for 6 months.Before and after treatment of serum BNP,color Doppler ultrasound to monitor the left ventricular end systolic diameter (LVDs),left ventricular end-diastolic diameter(LVDd),left atrial diameter (LAD),interventricular septum thickness(IVsT),left ventricular posterior wall thickness(LVPwT).ResultPilot group of 40 patients with chronic renal failure in maintenance hemodialysis patients after treatment IVsT,LVPwT significantly reduced compared with pre-treatment differences were significant(P<0.05);after treatment in patients with BNP,LVDs,LVDd,LAD and treatment of pre-There was no significant difference compared(P>0.05),control group data before and after treatment were not statistically significant(P>0.05). Conclusion:Tongmai Oral Solution can significantly improve Cardiac structures and functions in hemodialysis patients...