Comparison Of APACHEⅡ,MODS,SOFA And LODS Scores On Predicting Outcome Of Svere Acute Pancreatitis

ObjectTo compare acute physiological and chronic health evaluation(APACHEⅡ), Multiple Organ Dysfunction Score(MODS score),the Sequential-Organ Failure Assessment(SOFA score) and the Logistic Organ Dysfunction Score(LODS score) scores for predicting hospital mortality in severe acute pancreatitis.MethodsWith a diagnosis of severe acute pancreatitis 91 patients admitted to the ICU were enrolled.Admission APACHEⅡ(24h),MODS,SOFA,LODS scores and maximum MODS,SOFA,LODS scores were calculated and compared regarding hospital mortality.The prognostic ability of these four scoring systems were assessed by the areas under the receiver operating characteristic curves(AUC).ResultsThe AUC of admission scores were 0.758±0.052 for APACHEⅡ,0.785±0.049 for MODS,0.850±0.040 for SOFA,0.886±0.036 for LODS in predicting hospital mortality.And the AUC of maximum scores were 0.891±0.037 for MODS, 0.939±0.028 for SOFA,0.943±0.025 for LODS.All maximum scores had better ability in predicting hospital morality than the admission scores respectively(P＜0.05).In admission scores,the admission LODS show better power than APACHEⅡto predict hospital motality,while there were no significant difference among the MODS,SOFA and LODS.In maximum scores,SOFA show better power than MODS(P＜0.05),but there is no significant difference between the SOFA and LODS(P＞0.05).ConclusionIn predicting hospital mortality of the patients with severe acute pancreatitis, organ dysfunction scores(MODS,SOFA,LODS) show better power than APACHEⅡin predicting hospital mortality.And in organ dysfunction scores,the maximum scores show more ability than admission to predict outcome,especially the SOFA and the LODS scores.